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陳志豪 副教授兼科主任

一、基本資料                            

 

中文姓名

陳志豪

英文姓名

Chi-Ho       Chan

聯絡電話

(公)04-24730022轉11632

 

傳真號碼

04-24727178

E-MAIL

chiho@csmu.edu.tw

             

 

 

二、主要學歷

 

畢/肄業學校

國別

主修學門系所

學位

起訖年月

國立陽明大學

中國

微生物暨免疫學研究所

博士

1993/9 至1999/6

國立中興大學

中國

獸醫學研究所

碩士

1987/9至1989/6

國立中興大學

中國

獸醫系

學士

1982/9 至1987 /6

 

 

三、現職及與專長相關之經歷

 

服務機關

服務部門/系所

職稱

起訖年月

現職: 中山醫學大學

醫學系微生物及免疫學科

副教授

2007/12~

中山醫學大學

醫學系微生物及免疫學科

主任

2013/8~

中華民國台灣懷愛協會

 

監事(第六屆)

2015/4~

經歷:

 

 

 

中華民國台灣懷愛協會

 

秘書長(第二至五屆)

2003/1至2015/3

中山醫學大學附設醫院

臨床病毒研究中心

主任

2003/5~2007/12

 

中山醫學大學

醫學系微生物科

助理教授

1999/10至2007/11

中山醫學大學

醫學系微生物科

講師

1991/8至1999/9

中山醫學大學

醫學系微生物科

助教

1990/4至1991/7

國立中興大學

獸醫學研究所

助理

1989/7至1990/4

 

 

 

 

四、專長

 

1.病毒學

2.免疫學

3.微生物學

4.生物資訊

5.分子流行病學

 

 

 

 

 


 

五、榮譽及獎勵

  1. 在『微免與感染雜誌』Vol. 36 No.2所發表的論文『 台灣地區口腔病原菌對抗生素抗藥性之研究』榮獲93年度『養樂多文教基金會』優良論文獎。
  2. 在『微免與感染雜誌』Vol. 37 No.3所發表的論文『1997至2001年間台灣B型流感病毒的演化分析』榮獲94年度『養樂多文教基金會』特優論文獎。
  3. 在『微免與感染雜誌』Vol. 39 No.5所發表的論文「不同B型流感病毒株在神經母細胞瘤細胞株及神經膠質瘤細胞株之感染特性」獲96年度『養樂多文教基金會』特優論文獎。
  4. 在『微免與感染雜誌』Vol. 41 No.3所發表的論文『2004年台灣禽流感與豬流感的監測』榮獲97年度『養樂多文教基金會』特優論文獎。

六、研究領域

  1. 流行性感冒病毒株的基因分析。
  2. 建立流行性感冒病毒診斷晶片。
  3. 建立呼吸道病毒快速診斷技術。
  4. 建立口腔細菌定量PCR技術。
  5. 利用小白鼠檢測健康食品的免疫功能。
  6. 中藥抗病毒的研究。

 

七、研究計畫

  1. 輔導建立水果酵素製程檢驗平台。計畫編號:104-產學04
  2. 牙周病相關口腔病原菌基因體資料庫建置。計畫編號:PU/CSMU 102-1
  3. 建立中藥抗流感病毒之篩選平臺-藥效及作用機制病之評估(2-2。計畫編號:CCMP 100-RD-120
  4. 建立中藥抗流感病毒之篩選平臺-藥效及作用機制之評估(2-1。計畫編號:99-衛署04
  5. HAI titer test 測試計畫(產學)。計畫編號:99-產學01
  6. 血球凝集抑制測試計畫(產學)。計畫編號:98-產學18
  7. 病毒性感染症合約實驗室,共補助二年。計畫編號:CDC96-RD-010
  8. 疾病管制局九十五年度流感疫苗研究發展計畫--流行病學分支計畫: 『我國流感病毒抗體監測系統之建立』,共補助三年。計畫編號:DOH95-DC-1403
  9. 病毒性感染症合約實驗室。計畫編號:CDC95-RD-011
  10. 比較2004-2005夏季與冬季B型流感病毒分離株之基因差異。計畫編號:CSH-94-22
  11. 不明原因肺炎的致病原之探討。計畫編號:CSMU 94-OM-B-028
  12. 流感病毒預防及控制─圖譜、基因序列的建立(中南部地區)及相關研究。計畫編號:NSC 93-2317-B-040-001
  13. 豬群禽流感之監控與其對公共衛生上影響之研究 (II) 。計畫編號:DOH93-DC-1108
  14. 從細菌培養陰性腦膜炎及腦炎病人腦脊髓液中篩檢潛藏病毒基因。計畫編號:NSC 92-2314-B-040-030
  15. A型流感病毒H1N1亞型的基因分析。計畫編號:CSH-92-004
  16. 社區型肺炎之病因探討。補助編號:CSMU 93-OM-B-033
  17. 從老年人分離到A型流感病毒的鑑定與基因分析。計畫編號:CSH-93-005

八、論文發表

  1. 期刊論文
  1. Lee YT, Chen SC, Chan KC, Wu TC, Tsao SM, Chan CH*. 2013. Impact of infectious etiology on the outcome of hospitalized patients with community acquired pneumonia in a Taiwan Tertiary-care Hospital Experience. The Journal of Infection in Developing Countries 7: 116-124. (SCI)
  2. Hung HC, Chan CH, Tsao SM, Chen SC, Wu TC, Lu MC, Wu DJ, Huang SJ, Lee YT. 2012. Effectiveness of the BDProbeTec ET system for detection of Mycobacterium tuberculosis complex in sputum and bronchoalveolar lavage specimens. Brazilian Journal of Infectious Diseases 16: 242-249. (SCI)
  3. Liu WT, Chan CH*, SR Hsieh, YC Li. 2011. The challenge of AIDS vaccine development. Central Taiwan Journal of Humanities and Social Sciences 22: 81-91.
  4. Y. H. Hsieh* and C. H. Chan. 2011. Excess Healthcare Burden during 1918-1920 Influenza Pandemic in Taiwan: Implications for Post-pandemic Preparedness. BMC Public Health 11:41. (SCI)
  5. Yang, S. F., B. S. Tzang, K. T. Yang, Y. C. Hsiao, Y. Y. Chang, C. H. Chan, S. G. Fu, Y. C. Chen. 2010. Taurine alleviates dyslipidemia and liver damage induced by a high-fat/cholesterol-dietary habit. Food Chemistry 120: 156–162.
  6. Shieh, H. K., P. C. Chang, T. H. Chen, K. P. Li, C. H. Chan*. 2008. Surveillance of avian and swine influenza in the swine population in Taiwan, 2004. Journal of Microbiology, Immunology and Infection. 41: 231-242. (SCI expanded)
  7. Chan, Y., T. Chang , C. H. Chan, Y. C. Yeh, C. W. Chen, B. H. Shieh, C. Li. 2007. Immunomodulatory effects of Agaricus blazei Murill on Balb/cByJ mice. Journal of Microbiology, Immunology and Infection. 40: 201-208. (SCI expanded)
  8. Chan C. H.,* K. L. Lin, Y. Chan, Y. L. Wang, Y. T. Chi, H. L. Tu, H. K. Shieh, W. T. Liu. 2006. Amplification of the entire genome of influenza A virus H1N1 and H3N2 subtypes by reverse-transcription polymerase chain reaction. Journal of Virological Methods. 136: 38-43. (SCI)
  9. Wu, C. S. and C. H. Chan*. 2006. Clinical therapy of low-level laser irradiation on herpes simplex viruses. Journal of Laser in Dentistry 2: 33-41.
  10. Liu, Y. H., W. C. Liu, C. L. Guo, C. H. Chan*. 2006. The inhibition effect and related mechanism of diode 808nm GaAIAS laser on the proliferation of human carcinoma cells. Journal of Laser in Dentistry 2: 7-18.
  11. K. S. Wang, S. H. Chang, J. W. Wang, C. H. Chan*. 2005. A male accessory gland protein (MAG-317) in Aedes aegypti (L.): isolation, aminoterminal sequence determination and localization. Chung Shan Med. J. 16: 195-208.
  12. Chan C. H., Y. T. Lee, H. R. Chang, Y. Chan, W. T. Liu*. 2006. Characterization of various strains of influenza B virus in neuroblastoma cell line and glioblastoma cell line. Journal of Microbiology, Immunology and Infection. 39: 380-386. (SCI expanded)
  13. Chan C. H., Y. Chan, H. K. Shieh, C. H. Tsai, C. Y. Chen, S. C. Liu, W. T. Liu*. 2004. Phylogenetic analysis of influenza B virus in Taiwan during 1997-2001. Journal of Microbiology, Immunology and Infection 37: 135-144. (SCI expanded)
  14. Chang, H. R., J. D. Lian, C. H. Chan, L. C. Wong. 2004. Cytomegalovirus ischemic colitis of a diabetic renal transplant recipient. Clinical Transplantation18: 100-104. (SCI)
  15. Chan. Y., C. H. Lai, H. W. Yang, Y. Y. Lin and C. H. Chan*. 2003. The evaluation of Chinese herbal medicine effectiveness on periodontal pathogens. American Journal of Chinese Medicine. 31: 751-761. (SCI)
  16. Chan. Y. and C. H. Chan*. 2003. Antibiotic resistance of pathogenic bacteria from odontogenic infections in Taiwan. Journal of Microbiology, Immunology and Infection 36: 105-110. (SCI expanded)
  17. Yeh, C. S., H. C. Hu, C. H. Chan*. 2002. A study of the effect of different wavelength low energy laser irradiation after acupotomy. Journal of Laser in Dentistry 1: 52-58.
  18. Chan, C. H. 2001. Detection of nonstructural gene of influenza A virus from wild waterfowl in Datu estuary area. Chung Shan Med. J. 12: 35-45.
  19. Chan, C. H., M. C. Wu, C. T. Huang, K. G. Wu, and W. T. Liu*. 1999. Genetic characterization of the hemagglutinin of two strains of influenza B virus co-circulated in Taiwan. Journal of Medical Virology 59: 208-214. (SCI)

*Corresponding author

 

(B)研討會論文

  1. Chan CH and Liu WT*. Genotyping of influenza B viruses by double-strand conformationpolymorphism. The XIth International Congress of Virology, Sydney, Australia 1999.
  1. Chan CH and Liu WT*. Study of the pathogenesis of neurotropic influenza B virus strains in Taiwan. Options for the control of influenza IV. Hersonissos, Crete, Greece 2000.
  2. Chan CH, Kuo RL, Tsai CH, Chen CY, Liu SC, and Liu WT*. A new cluster of influenza B virus prevalence in Taiwan during 1997-2001. The XIIth International Congress of Virology, Paris, France 2002.
  3. Wang YL, Chi YT, Lin KL, Lin YH, Chan CH*. 2003. Detection and molecular characterization of influenza virus genes in cerebrospinal fluid of central nervous system infection. Options for the control of influenza V. Okinawa, Japan 2003.
  4. Houng HSH, Sun W, Shih MC, Chan CH, Lin MT. 2003. Utilizing standard amplification efficacy to develop an efficient real-time SARS coronavirus RT-PCR assays for early detection of the SARS coronavirus infections in Taiwan. Options for the control of influenza V. Okinawa, Japan 2003.
  5. Wang YL, Chi YT, Lin KL, Lin YH, Chan CH*. 2003. Diagnostic study of various virus infections in the patients of central nervous system infection in Taiwan. The 6th Chinese Laboratory Medicine Conference, Hong Kong 2003.
  6. Chan CH. 2003. The mission of Clinical Virology and Research Center. The 1st Clinical Virology Conference of Central Taiwan, Chung Shan Medical University Hosptial, Taichung, Taiwan 2003.
  7. Wang YL, Chi YT, Lin KL, Lin YH, Chan CH*. 2003. Diagnostic study of various virus infections and composition of chemokines in cerebrospinal fluid of central nervous system infection patients. The 37th Annual Meeting of the Chinese Society of Microbiology 2003.
  8. Chan CH, Lin KL, Chan Y, Wang YL, Chi YT, Tu HL, Shieh HK, Liu WT*. 2005. Amplification of the entire influenza A virus genome by high temperature reverse-transcription polymerase chain reaction. APEC Conference on Avian Influenza, 2005.
  1. Chang PC, Chan CH, Chen TH, Chang CC, Shieh HK. 2005. Surveillance on avian influenza in swine population and studies on its relationship with public health. APEC Conference on Avian Influenza, 2005.
  2. Chan CH, Lin KL, Wang YL, Chi YT, Lin YH, Tu HL, Shieh HK, Liu WT*. Amplification of the entire influenza A virus genome by reverse-transcription polymerase chain reaction. XIII International Congress of Virology, San Francisco, USA, 2005.
  3. Tsao SM, Lee YT, Liu KS, Chi YT, Lee CW, Chen CY, Chan CH*. Analysis and surveillance of the etiology of community acquired pneumonia. The Seventh Chinese Laboratory Medicine Conference in Taipei, 2005.
  4. CR Chen, YC Chen, YT Chi, SM Tsao, YT Lee, KS Liu, SF Yu, HS Lee, PS Hsu, CH Chan*. Antibody responses to influenza vaccination in adults and elderly in Taiwan, 2006. Options for the Control of Influenza VI, Toronto, Canada, 2007.
  5. Chen WL, Chi YT, Chiou HL, Chan CH *. Detection of enterovirus gene in cerebrospinalfluid by CODEHOP RT sn-PCR. Asia-Pacific Medical Laboratory Science Forum,Taichung City, Taiwan, 2008.
  6. Chen CR, Chen YC, Chi YT, Tsao SM, Lee YT, Liu KS, Yu SF, Lee HS, Hsu PS, Chan CH*.Evaluation of the efficacy and immunity of influenza vaccination in adult and elderly people.11th Western Pacific Congress on Chemotherapy and infectious diseases, Taipei City,Taiwan, 2008.
  7. Tsai PH, Chi YT, Chan CH *. Establishment of a platform to screen Chinese herbal medicines against influenza viruses. Options for the Control of Influenza VII, Hong Kong, 2010.
  8. Tsai PH, Chen BC, Lee MS, Ho TY, Chan CH *. Establishment of a platform with embryonated chicken egg to screen traditional Chinese medicine against influenza viruses. The 20th Annual Meeting of the Taiwan Society of Microbiology 2010.
  9. 陳俊瑋,洪粕宸,張振平,陳志豪,賴全裕*。2011。活性碳濾材之營養源、回潮率與含水率對細菌存活率影響探討。2011年工業衛生暨環境職業學術研討會,中台科技大學,台中,台灣,4月23日~24日。
  10. Chan CH *, Lee YT, Lee MP, Chou MC, Tsai TP. Retrospective surveillance of AIDS and syphilis in general population, gay sauna and academic gay society, 2002-2010. International Conference on Global Health and Public Health Education, Hong Kong 2011.
  11. Chan CH *, Tsai TP, Wu CF, Wong PF, Yim SY, Lee MS, Ho TY. Establishment of screening platform of traditional Chinese medicine for anti-influenza drugs: evaluation of the effect. The 21st Annual Meeting of the Taiwan Society of Microbiology, National Cheng Kung University, Taiwan 2011.
  12. Su SY, Huang HC, Ho TY, Chan CH *. Evaluation traditional Chinese medicines for anti-influenza virus activities. 2012 International Symposium on RNA Viruses. Chang Gung University, Taiwan 2012.
  13. Su SY, Huang HC, Ho TY, Chan CH *. Evaluation traditional Chinese medicines for anti-influenza virus activities. The 20th Annual Meeting of the Taiwan Society of Microbiology, National Cheng Kung University, Taiwan 2012.
  14. Wu MS, Lai CY, Chan CH *. Evaluation of sampling efficiency of virus-containing bioaerosols for detection of influenza viruses. The 20th Annual Meeting of the Taiwan Society of Microbiology, National Cheng Kung University, Taiwan 2012.
  15. 王孟優,許惠臻,陳志豪,徐慶琳,李衛民,賴全裕*。2013。動物醫院生物氣膠特性及其抗藥性評估。台灣微生物學會第二十一次會員大會暨學術研討會。
  16. Chan CH *, Chan YH, Chan Y, Lin KL. 2014. Phylogenetic analysis of the 16S rRNA gene of Porphyromonas gingivalis clinical isolates. The 21st Annual Meeting of the Taiwan Society of Microbiology, National Cheng Kung University, Taiwan 2014.
  17. Chan CH *, Chan YH, Chan Y, Lin KL. 2015. Diversity of 16S rRNA and Arg-gingipain A genes of Porphyromonas gingivalis clinical isolates. The 21st Annual Meeting of the Taiwan Society of Microbiology, Taipei International Convention Center, Taiwan 2015.

 

(C)專書及專書論文

  1. Chan CH. The surveillance of avian influenza in Taiwan, R.O.C. M.S. Thesis. Department of Veterinary Medicine, National Chung Hsing University, 1989.
  2. Chan CH. Gene analysis of influenza A and B isolates. Ph.D Thesis. Institute of Microbiology and Immunology, National Yang Ming University, 1999.

 

九、其他學術事項

  1. 陳志豪老師代表中山醫學大學協辦『APEC Conference on Avian Influenza』日期:2005/6/22-23地點:國立中興大學獸醫學院診斷中心

 

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