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本科十分重視學術研究,因此鼓勵醫師從事研究工作及在職進修醫學研究所,並鼓勵醫師參加國內外醫學會論文或個案報告,以增進學術交流。最近五年發表於國內外知名醫學雜誌期刊,以及參加國內外醫學論文報告如下 :




1.          Wang YH, Ku MS, Sun HL, Lue KH*. Efficacy of nasal irrigation in the treatment of acute sinusitis in atopic children. J Microbiol Immunol Infect. 47:63-69 2014 (SCI)


2.          Tsai JD, Kuo HT, Chen SM, Lue KH*, Sheu JN*. Neurological Images and the Predictors for Neurological Sequelae of Epidemic Herpangina/Hand-Foot-Mouth Disease with Encephalomyelitis. Neuropediatrics. in press 2013 (SCI).


3.          Chang YC, Hsiao YM, Wu MF, Ou CC, Lin YW, Lue KH*, Ko JL*. Interruption of Lung cancer cell migration and proliferation by fungal immunomodulatory protein FIP-fve from flammulina velutipes. J Agric Food Chemistry. 61:12044-12052 2013 (SCI)


4.          Sun HL, Wu KH, Chen SM, Chao YH, Ku MS, Hung TW, Liao PF, Lue KH, Sheu JN. Role of procalcitonin in predicting dilating vesicoureteral reflux in young children hospitalized with a first febrile urinary tract infection. Pediatr Infect Dis J. 32(9):e348-e354 2013 (SCI)


5.          Yang JS, Lin CW, Hsieh YS, Cheng HL, Lue KH, Yang SF, Lu KH. Selaginella tamariscina (Beauv.) possesses antimetastatic effects on human osteosarcoma cells by decreasing MMP-2 and MMP-9 secretions via p38 and Akt signaling pathways. Food Chem Toxicol. 59:801-807 2013 (SCI=3.01)


6.          Mak KK, Ku MS, Lu KH, Sheu JN, Sun HL, Lue KH*. Comparison between Mometasone Furoate Monohydrate (Nasonex) and Fluticasone Propionate (Flixonase) nasal sprays in the treatment of childhood perennial allergic rhinitis.  Pediatr Neonatol. 54:239-245 2013 (SCI)


7.          Tsai JD , Chang SN, Mou CH, Sung FC* , Lue KH*. Association between Atopic Diseases and Attention-deficit / Hyperactivity Disorder in Childhood: A Population-Based Case-Control Study. Annals of Epidemiology. 23:185-188 2013(SCI)


8.          Lu KH, Yang HN, Su CW, Lue KH, Yang SF, Hsieh YS.  Phyllanthus urinaria suppresses human osteosarcoma cell invasion and migration by transcriptionally inhibiting u-PA via ERK and Akt signaling pathways. Food Chem Toxicol 52:193–199 2013 (SCI)


9.          Sheu JN, Wu KH, Chen SM, Tsai JD, Chao YH, Lue KH.  Acute 99mTc DMSA Scan Predicts Dilating Vesicoureteral Reflux in Young Children With a First Febrile Urinary Tract Infection: A Population-Based Cohort Study. Clinical Nuclear Medicine 38(3):163-168 2013 (SCI)


10.      Lee YT, Lee SS, Sun HL, Lu KH, Ku MS, Sheu JN, Ko JL*, Lue KH*. Effect of the fungal immunomodulatory protein FIP-fve on airway inflammation and cytokine production in mouse asthma model. Cytokine. 61:237-244 2013 (SCI:3.019; 68/139=49% Immunology)


11.      Hsieh MY, Ku MS, Tsao TF, Chen SM, Chao YH, Tsai JD, Lue KH, Sheu JN. Rare case of atrophic ectopic kidney with giant hydronephrosis in a 7-Year-Old Girl. Urology. 81:655-658 2013 (SCI)


12.      Chen SM, Chang HM, Hung TW, Chao YH, Tsai JD, Lue KH, Sheu JN. Diagnostic performance of procalcitonin for hospitalised children with acute pyelonephritis presenting to the paediatric emergency department. Emerg Med J online 2012. (SCI)


13.      Ku MS, Sun HL, Sheu JN, Lee HS, Yang SF*, Lue KH*. Neonatal jaundice is a risk factor of childhood asthma: a retrospective cohort study. Pediatr Allergy Immunol 23:623-8, 2012 (SCI)


14.      Hsin IL, Sheu GT, Jan MS, Sun HL, Wu TC, Chiu LY, Lue KH*, Ko JL*. Inhibition of lysosome degradation on autophagosome formation and responses to GMI, an immunomodulatory protein from Ganoderma microsporum. Br J Pharmacol 167:1287-300, 2012. (SCI) (IF:4.409, 35/261 Phamacology)3*5*5


15.      Ku MS, Lue KH, Sun HL* The ten leading causes for adolescent ambulatory visits and major health care providers. Pediatr I. 2012 (IF:0.755, 88/109 Pediactrics ) 3*2*3=18


16.      Sun HL, Yeh CJ, Ku MS, Lue KH. Co-existence of Allergic Diseases: Patterns and Frequencies. Allergy Asthma Proc. 33(1):177-81,2012. (SCI)


(IF:1.735,12/21 Allergy)3*3*0.5=3


17.      Ku MS, Lue KH, Lee SS, Sun HL* Preliminary report on admission profiles for children under 5 years old in Taiwan: 2000 and 2009 disparities Pediatr Neonatol 53(4): 221-7, 2012. (SCI) (IF:0.747, 89/109 Pediactrics 89/107) 3*1.5*1=4.5


18.      Hsu CH, Hu CM, Lu KH, Yang SF, Tsai CH, Ko CL, Sun HL*, Lue KH*. Effect of Selective Cysteinyl Leukotriene Receptor Antagonists on Airway Inflammation and Matrix Metalloproteinase Expression in a Mouse Asthma Model. Pediatr Neonatol 53: 235-44, 2012 (SCI) (IF:0.747, 89/109 Pediactrics)3*1.5*5*=22.5


19.      Lue KH*, Sun HL, Lu KH, Ku MS, Sheu JN, Chan CH, Wang YH. A trial of adding Lactobacillus johnsonii EM1 to levocetirizine for treatment of perennial allergic rhinitis in children aged 7–12 years. Int J Pediatr Otorhi. 76:994-1001 2012. (SCI) (IF: 1.067, 39/109 Pediatrics)3*4*5=60)


20.      Liu YF, Chang SH, Sun HL, Chang YC, Hsin IL, Lue KH*, Ko JL*. IFN-γ Induction on Carbohydrate Binding Module of Fungal Immunomodulatory Protein in Human Peripheral Mononuclear Cells. J Agric Food Chem 60:4914–22, 2012 (SCI) (IF;2.816 73/128, Food Science & Technology)3*3*5


21.      Chu WY, Tsao TF, Chen SL, Chang HM, Chen SM, Chen CY, Lue KH, Sheu JN. A 12-year-old boy with an infected ectopic ureter presenting with acute appendicitis-like symptoms and acute scrotum. Scan J Urol Nephrol 46:208-11, 2012. (SCI:1.293; 49/69=71%; 3x2x0.5)


22.      Pan HH, Chang HM, Chen SM, Hung TW, Lue KH, Sheu JN. Life-Threatening Rhabdomyolysis Induced by Streptococcus bovis Sepsis in a 6-Year-Old Girl Presented to the Pediatric Emergency Department. Pediatr Emerg Care 28(5):469-71, 2012. (SCI:0.782; 16/24=67%)


23.      Sun HL, Yeh CJ, Ku MS, Lue KH. Co-existence of Allergic Diseases: Patterns and Frequencies. Allergy Asthma Proc. 33(1):177-81, 2012. (SCI)


24.      Lin SW, Wang YH, Lee MY, Ku MS, Sun HL, Lu KH, Lue KH*. Clinical spectrum of acute rhinosinusitis among atopic and nonatopic children in Taiwan. Int J Pediatr Otorhi. 76:70-75, 2012. (SCI) ( IF: 1.067, 39/109 Pediatrics)3*4*5=60


25.      Chen CY, Tsao TF, Chang HM, Chen SL, Chen SM, Hung TW, Lue KH, Sheu JN. Bladder agenesis and bilateral ectopic ureters draining into the vagina in a female infant: demonstrated by MR imaging. Surg Radio Anat. 34:89-92, 2012 (SCI) (IF:0.827, 169/188 Surgery)3*1.5*0.5=2.25


26.      Liao PF, Ku MS, Lue KH, Sun HL* Respiratory tract infection is the major cause of the ambulatory visits in children. Italian Journal of Pediatrics 37:43,2011. (MI)3*0.5*1=1.5


27.      Hsin IL, Ou CC, Wu TC, Jan MS, Wu MF, Chiu LY, Lue KH*, Ko JL*. GMI, an immunomodulatory protein from Ganoderma microsporum, induces autophagy in non-small cell lung cancer cells. Autophagy. 7:8, 1-10, 2011 (SCI) 


(IF:12.042, 12/185 Cell Biology) 3*24.084*5=361.26


28.      Sheu JN, Chang HM, Chen SM, Hung TW, Lue KH. The role of procalcitonin for acute pyelonephritis and subsrquent renal scarring in infants and young children. J Urology. 186:2002-2008, 2011 (SCI) ( IF;3.862, 36/69 Urology & Nephrology) 3*3*0.5=4.5


29.      Ku MS, Sun HL, Lu KH, Sheu JN, Lee HS, Yang SF*, Lue KH*. The CC16 A38G polymorphism is associated with the development of asthma in children with allergic rhinitis. Clinical & Experimental Allergy. 41:794–800, 2011 (SCI) ( IF:4.195 3/21 Allergy)3*5*5*0.8=60


30.      Lin CH, Hsiao YM, Ou CC, Lin YW, Chiu YL, Lue KH, Chang JG, Ko JL. GMI, a Ganoderma Immunomodulatory Protein, Down-regulates Tumor Necrosis Factor r-Induced Expression of Matrix Metalloproteinase 9 via NF-KB Pathway in Human Alveolar Epithelial A549 Cells. J Agric Food Chem 58:12014–12021, 2010 (SCI) (IF;2.816 73/128, Food Science & Technology)3*3*0.5=4.5


31.      Quek YW, Sun HL, Ng YY, Lee HS, Yang SF, Ku MS, Lu KH, Sheu JN, Lue KH*. Associations of serum leptin with atopic asthma and allergic rhinitis in children. Am J Rhinol Allergy 24:354-358, 2010. (SCI)  


(IF;1.881 9/41, Otorhinolarygology)3*4*5=60


32.      Chu SC , Yang SF, Tzang BS, Hsieh YS, Lue KH, Lu KH. Cathepsin B and cystatin C play an inflammatory role in gouty arthritis of the knee. Clinica Chimica Acta 411:1788-1792, 2010. (SCI) (IF:2.389, 15/31 Medical Laboratory Technology)3*3*0.5=4.5


33.      Chou Kuo TN, Li YS, Lue KH, Liao CF, Lin CY, Tzeng PR, Wong RH. Genetic Polymorphism of Manganese Superoxide Dismutase is Associated with Childhood Asthma. J Asthma 47:532-538, 2010. (SCI)


(IF:1.341, 17/21 Allergy )3*2*1=6


34.      Law YY, Lue KH, Lu KH. Gouty Tophi Presenting as Medial Patellar Plica Syndrome and Patellofemoral Disorder to Limit Knee Range of Motion. J Rheumatol 370(3):680-681, 2010. (SCI)


         (IF:3.551, 14/29 Rheumatology )3*3*3=27