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1984/09 1991/06





1993/09 1996/01





1999/09 2004/06

 三、 現職及與專長相關之經歷








2009/08 迄今




2006/08 迄今




1998/07 迄今








1994/07 1995/6




1996/07 1998/6

四、專長 請自行填寫與研究方向有關之專長學門。

1.       新陳代謝科

2.       內分泌學

3.       內分泌分子生物學





l The anti-atherosclerotic mechanism by statin or alternative medicine
Chan KC, Wang CJ, Ho HH, Chen HM, Huang CN*. Simvastatin inhibits cell cycle progression in glucose-stimulated proliferation of aortic vascular smooth muscle cells by up-regulating cyclin dependent kinase inhibitors and p53. Pharmacol Res. 2008; 58(3-4):247-56. (SCI *Correspondence)
2. Huang CN, Chan KC, Lin WT, Su SL, Wang CJ, Peng CH. Hibiscus sabdariffa Inhibits Vascular Smooth Muscle Cell Proliferation and Migration Induced by High Glucose-A Mechanism Involves Connective Tissue Growth Factor Signals. J Agric Food Chem. 2009 Mar 20. [Epub ahead of print] (SCI)
3. Chan KC, Chou HH, Huang CN*, Chou MC. Atorvastatin administration after percutaneous coronary intervention in patients with coronary artery disease and normal lipid profiles: impact on plasma adiponectin level. Clin Cardiol. 2008; 31(6):253-8. (SCI *Correspondence)
4. Huang CN, Liu KL, Cheng CH, Lin YS, Lin MJ, Lin TH. PGE2 enhances cytokine-elicited nitric oxide production in mouse cortical collecting duct cells. Nitric Oxide. 2005; 12(3):150-8. (SCI)
5. Hsieh CL, Huang CN, Lin YC, Peng RY. Molecular action mechanism against apoptosis by aqueous extract from guava budding leaves elucidated with human umbilical vein endothelial cell (HUVEC) model. J Agric Food Chem. 2007; 55(21):8523-33. (SCI)l  Mathematical model simulation on insulin secretion or hypertension
6. Huang CN, Chou WC, Lin LY, Peng CC, Chyau CC, Chen KC, Peng RY. First phase release coefficient of insulin in subjects with normal glucose tolerance on glucose infusion analyzed by computer simulation. Biosystems. 2008; 91(1):146-57. (SCI)
7. Huang CN, Peng CH, Shih CM, Chiu WT, Chayu CC, Chen KC, Peng CC, Peng RY. Fluid mechanical and physicochemical modeling interprets hypertension to be capable of inducing secondary complications. Med Hypotheses. 2007;68(5):967-78. (SCI) l   Candidate genes studies on DM or Graves’ disease 
8. Chang YH, Huang CN, Wu CY, Shiau MY. Association of interleukin-10 A-592C and T-819C polymorphisms with type 2 diabetes mellitus. Hum Immunol. 2005; 66(12):1258-63. (SCI)
9. Shiau MY, Huang CN, Yang TP, Hwang YC, Tsai KJ, Chi CJ, Chang YH. Cytokine promoter polymorphisms in Taiwanese patients with Graves' disease. Clin Biochem. 2007; 40(3-4):213-7. (SCI)l   Studies of metabolic syndrome and the relation between surrogate markers and diabetic complications
10.  Ting H, Lo HS, Chang SY, Chung AH, Kuan PC, Yuan SC, Huang CN*, Lee SD. Post- to pre-overnight sleep systolic blood pressures are associated with sleep respiratory disturbance, pro-inflammatory state and metabolic situation in patients with sleep-disordered breathing. Sleep Med. 2008. (SCI *Correspondence)
11.  Yang YS, Peng CH, Lin CK, Wang CP, Huang CN*. Use of serum cystatin C to detect early decline of glomerular filtration rate in type 2 diabetes. Intern Med. 2007; 46(12):801-6. (SCI *Correspondence)
12. Sia SK , Yang YS, Ueng KC, and Huang CN*. Peroxisome proliferator-activated receptors (PPARs) and agonists: review of literatures. Journal of Internal Medicine of . 2008; 19(1): 14-26. (*Correspondence)
13.  Lee IT, Lee WJ, Ou HC, Huang CN, Sheu WH. Metabolic syndrome abating the beneficial effect of pravastatin treatment on adhesion of endothelium by monocytes in subjects with hypercholesterolemia. Metabolism. 2009; 58(3):416-20. (SCI)
14.  Lee IT, Huang CN, Lee WJ, Lee HS, Sheu WH. Aggravation of albuminuria by metabolic syndrome in type 2 diabetic Asian subjects. Diabetes Res Clin Pract. 2008; 81(3):345-50. (SCI)
15.  Lee IT, Huang CN, Lee WJ, Lee HS, Sheu WH. High total-to-HDL cholesterol ratio predicting deterioration of ankle brachial index in Asian type 2 diabetic subjects. Diabetes Res Clin Pract. 2008;79(3):419-26. (SCI)
16.  Lee IT, Lee WJ, Huang CN, H-H Sheu W. The association of low-grade inflammation, urinary albumin, and insulin resistance with metabolic syndrome in nondiabetic Taiwanese. Metabolism. 2007; 56(12):1708-13. (SCI)
l  Epidemiology opinions about diabetes as a cause of mortality
17.  Lu TH, Walker S, Johansson LA, Huang CN*. An international comparison study indicated physicians' habits in reporting diabetes in part I of death certificate affected reported national diabetes mortality. J Clin Epidemiol. 2005; 58(11):1150-7. (SCI *Correspondence)
18.  Lu TH, Lai MS, Anderson RN, Huang CN*. Diabetes reporting as a cause of death: results from the Translating Research Into Action for Diabetes (TRIAD) study: response to McEwen et al. Diabetes Care. 2007;30(5):e46. (SCI *Correspondence)
19.  Lu TH, Hsu PY, Anderson RN, Huang CN*. Mortality and causes of death in a national sample of diabetic patients in : response to Tseng. Diabetes Care. 2005; 28(5):1266-7. (SCI *Correspondence) l  Anti-tumor effect of herbal derivatives
20.  Peng CH, Huang CN, Hsu SP, Wang CJ. Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells. Toxicology. 2007; 238(2-3):130-9. (SCI)
21.  Peng CH, Huang CN, Hsu SP, Wang CJ. Penta-acetyl geniposide induce apoptosis in C6 glioma cells by modulating the activation of neutral sphingomyelinase-induced p75 nerve growth factor receptor and protein kinase Cdelta pathway. Mol Pharmacol. 2006; 70(3):997-1004. (SCI)
22.  Peng CH, Huang CN, Wang CJ. The anti-tumor effect and mechanisms of action of penta-acetyl geniposide. Curr Cancer Drug Targets. 2005; 5(4):299-305. (SCI)
23.  Peng CH, Tseng TH, Huang CN, Hsu SP, Wang CJ. Apoptosis induced by penta-acetyl geniposide in C6 glioma cells is associated with JNK activation and Fas ligand induction. Toxicol Appl Pharmacol. 2005; 202(2):172-9. (SCI)
24.  Hsu TC, Chiang SY, Huang CY, Tsay GJ, Yang CW, Huang CN, Tzang BS. Beneficial effects of treatment with transglutaminase inhibitor cystamine on macrophage response in NZB/W F1 mice. Exp Biol Med. 2007; 232(2):195-203. (SCI)
25.  Hsu TC, Tzang BS, Huang CN, Lee YJ, Liu GY, Chen MC, Tsay GJ. Increased expression and secretion of interleukin-6 in human parvovirus B19 non-structural protein (NS1) transfected COS-7 epithelial cells. Clin Exp Immunol. 2006; 144(1):152-7. (SCI)
l  Case reports and others
26.  Yeo KF, Yang YS, Chen KS, Peng CH, Huang CN*. Simultaneous presentation of thyrotoxicosis and diabetic ketoacidosis resulted in sudden cardiac arrest. Endocr J. 2007;54(6):991-3. (SCI *Correspondence)
27.  Sia SK, Huang CN, Ueng KC, Wu YL, Chan KC. Double vessel acute myocardial infarction showing simultaneous total occlusion of left anterior descending artery and right coronary artery. Circ J. 2008; 72(6):1034-6. (SCI)
28.  Yang YS, Peng CH, Sia SK, Huang CN*. Acquired hypophosphatemia osteomalacia associated with Fanconi's syndrome in Sjögren's syndrome. Rheumatol Int. 2007; 27(6):593-7. (SCI *Correspondence)
29.  Cadée JA, Chang CY, Chen CW, Huang CN, Chen SL, Wang CK. Bovine casein hydrolysate (c12 Peptide) reduces blood pressure in prehypertensive subjects. Am J Hypertens. 2007; 20(1):1-5. (SCI)
30.  Hsieh CL, Lin YC, Ko WS, Peng CH, Huang CN, Peng RY. Inhibitory effect of some selected nutraceutic herbs on LDL glycation induced by glucose and glyoxal. J Ethnopharmacol. 2005; 102(3):357-63. (SCI)
31.  Chen KC, Peng CC, Hsieh HM, Peng CH, Hsieh CL, Huang CN, Chyau CC, Wang HE, Peng RY. Antiandrogenic therapy can cause coronary arterial disease. Int J Urol. 2005; 12(10):886-91. (SCI)