急診醫學科主任：葉兆斌 教授

 

學歷

1982/09 -~1989/06   中山醫學大學 醫學系
1999/09 ~ 2001/06  中山醫學大學醫學研究所 醫學碩士
2007/09 ~ 2010/06  中山醫學大學醫學研究所 醫學博士

 

經歷

2008/02~2011/01  中山醫學大學醫學系    講師    

2011/02~2014 /01 中山醫學大學醫學系    助理教授 

2014/02~2017/01  中山醫學大學醫學系     副教授

2017/02~迄今         中山醫學大學醫學系     教授

2005/08~2008/07  中山醫學大學附設醫院 急診外科主任          

2008/08~迄今         中山醫學大學附設醫院 急診主治醫師

2013/08~迄今         中山醫學大學醫學系 急診醫學科科主任

 

專長　

急診醫學、重症醫學、創傷醫學、內視鏡醫學、外科醫學、消化系外科醫學

 

 

期刊論文

 

1.Lin HW, Hsieh MJ, Yeh CB, Hsueh KC, Hsieh YH, Yang SF*. Coronarin D induces apoptotic cell death through the JNK pathway in human hepatocellular carcinoma. Environmental Toxicology May,2018; in press. (SCI)

2.Yeh YT, Wang BY, Lin CW, Yang SF, Ho SW, Yeh HW, Huang JY, Chang YC*, Yeh CB*. Periodontitis and dental scaling associated with pyogenic liver abscess: A population-based case-control study. Journal of Periodontal Research May,2018; in press. (SCI)

3. Lee CY, Chen HC, Lin HW, Huang JY, Chao SC, Yeh CB, Lin HY*, Yang SF*. Blepharitis as an early sign of metabolic syndrome: A nationwide population-based study. British Journal of Ophthalmology May,2018; in press. (SCI)

4. Chien MH, Ho YC, Yang SF, Yang YC, Lai SY, Chen WS, Chen MJ*, Yeh CB*. Niclosamide, an oral antihelmintic drug, exhibits antimetastatic activity in hepatocellular carcinoma cells through downregulating Twist-mediated CD10 expression. Environmental Toxicology May,2018; 33: 659-669. (SCI)

5. Feng IC, Hsieh MJ, Chen PN, Hsieh YH, Ho HY, Yang SF, Yeh CB*. Cantharidic acid induces apoptosis through the p38 MAPK signaling pathway in human hepatocellular carcinoma. Environmental Toxicology Mar,2018; 33: 261-268. (SCI)  

6. Yang SF, Yeh CB*. Reply to: Proton Pump Inhibitors and Risk of Pneumonia in Individuals with Dementia. Journal of the American Geriatrics Society Nov,2017; 65: 2547-2548.

7. Hsu HW, Teng YH, Yeh CB, Ho SW*. Young Girl With Abdominal Pain. Annals of Emergency Medicine Oct,2017; 70: e39-e40.

8. Wang HL, Tsao SM, Yeh CB, Chou YE, Yang SF*. Circulating level of HMGB-1 predicts the severity of community-acquired pneumonia: modulation of inflammatory responses via JNK pathway in macrophages. Molecular Medicine Reports Sep,2017; 16: 2361-2366. (SCI)

9. Ho SW, Teng YH, Yang SF, Yeh HW, Wang YH, Chou MC, Yeh CB*. Association of proton pump inhibitors usage with risk of pneumonia in dementia patients. Journal of the American Geriatrics Society Jul,2017; 65: 1441-1447. (SCI)

10. Ho SW, Yeh CB, Yang SF, Yeh HW, Huang JY, Teng YH*. Pneumonia is an independent risk factor for pyogenic liver abscess: A population-based, nested, case-control study. PLoS ONE Jun,2017; 12: e0178571. (SCI)

11. Chen HW, Yeh YT, Tien DM, Yeh CB*. Major bleeding as spontaneous haemoperitoneum in a patient with factor V deficiency. Haemophilia Mar,2017; 23: e158-e16. (SCI)

12. Ho TH, Chang SW, Yeh HW, Yeh CB*. Occult perforation with circumferential ischaemic injury of the sigmoid colon following seat-belt trauma: a case report. Hong Kong Journal of Emergency Medicine Mar,2017; 24: 100-103. (SCI)

13. Sheu MJ, Hsieh MJ, Chou YE, Wang PH, Yeh CB, Yang SF, Lee HL, Liu YF*. Effects of ADAMTS14 genetic polymorphism and cigarette smoking on the clinicopathologic development of hepatocellular carcinoma. PLoS ONE Feb,2017; 12: e0172506. (SCI)

14. Huang WS, Lin HY, Yeh CB, Chen LY, Chou YE, Yang SF, Liu YF*. Correlation of chitinase 3-Like 1 single nucleotide polymorphisms with hepatocellular carcinoma in Taiwan. International Journal of Medical Sciences Feb,2017; 14: 136-142. (SCI)

15. Ho SW, Teng YH, Yang SF, Yeh HW, Wang YH, Chou MC, Yeh CB*. Risk of pneumonia in patients with isolated minor rib fractures: A nationwide cohort study. BMJ Open Dec,2016; 6: e013029. (SCI)

16. Lau HK, Hsieh MJ, Yang SF, Wang HL, Kuo WH, Lee HL, Yeh CB*. Association between Interleukin-18 polymorphisms and hepatocellular carcinoma occurrence and clinical progression. International Journal of Medical Sciences Jul,2016; 13: 556-561. (SCI)

17. Yang SF, Yeh CB, Chou YE, Lee HL, Liu YF*. Serpin peptidase inhibitor (SERPINB5) haplotypes are associated with susceptibility to hepatocellular carcinoma. Scientific Reports May,2016; 6: 26605. (SCI)

18. Wangh HL , Yeh CB, Lein MY, Su CM, Yang SF, Liu YF*, Tang CH*. Effects of HMGB1 polymorphisms on the susceptibility and progression of hepatocellular carcinoma. International Journal of Medical Sciences 2016; 13: 304-309. (SCI)

19. Chen TP, Lee HL, Huang YH, Hsieh MJ, Chiang WL, Kuo WH, Chou MC, Yang SF, Yeh CB*. Association of intercellular adhesion molecule-1 single nucleotide polymorphisms with hepatocellular carcinoma susceptibility and clinicopathologic development. Tumor Biology Feb,2016; 37: 2067-2074. (SCI)

20. Hsieh MJ, Yeh CB, Chiou HL, Hsieh MC*. Yang SF*. Dioscorea nipponica attenuates migration and invasion by inhibition of urokinase-type plasminogen activator through involving PI3K/Akt and transcriptional inhibition of NF-κB and SP-1 in hepatocellular carcinoma. American Journal of Chinese Medicine Feb,2016; 44: 177-195. (SCI)

21. Tsai YC, Tsai MC, Yeh CB, Ho SW*. Febrile Man with Pneumoperitoneum. Journal of Emergency Medicine Jan,2016; 50: e37-8.

22. Yeh YT, Ho SW, Liu YC, Yeh CB*. Blunt traumatic cardiac rupture presenting as massive hemothorax. Hong Kong Journal of Emergency Medicine Sep,2015; 22: 320-323. (SCI)

23. 5.Su SC, Hsieh MJ, Chou YE, Fan WL, Yeh CB*. Yang SF*. Effects of RAGE Gene Polymorphisms on the Risk and Progression of Hepatocellular Carcinoma. Medicine Aug,2015; 94: e1396. (SCI)  

24. Ho SW, Hsieh MJ, Yang SF, Yeh YT, Wang YH, Yeh CB*. Risk of stroke-associated pneumonia with acid-suppressive drugs: a population based cohort study. Medicine Jul,2015; 94: e1227. (SCI)

25. Ho SW, Yeh YT, Wu CH, Liu YC, Yeh CB*. Massive pulmonary embolism after overdose of oral benzodiazepine. Hong Kong Journal of Emergency Medicine Jul,2015; 22: 186-188. (SCI) 

26. Huang KY, Tsai MC, Yeh CB, Ho SW*. Spontaneous Rupture of Hepatocellular Carcinoma Mimicking ST-Segment Elevation Myocardial Infarction. Journal of Emergency Medicine Jun,2015; 48: e123-5. (SCI) 

27. Sheu MJ, Hsieh MJ, Chiang WL, Yang SF, Lee HL, Lee LM, Yeh CB*. Fibroblast growth factor receptor 4 polymorphism is associated with liver cirrhosis in hepatocarcinoma. PLoS ONE Apr,2015; 10: e0122961. (SCI)

28.Yeh CB, Yu YL, Lin CW, Chiou HL, Hsieh MJ, Yang SF. Terminalia catappa attenuates urokinase-type plasminogen activator expression through Erk pathways in Hepatocellular carcinoma. BMC Complement Altern Med. 2014 Apr 30;14(1):141. doi: 10.1186/1472-6882-14-141.(SCI)

29.Chiang TY, Tsao SM, Yeh CB, Yang SF. Matrix metalloproteinases in pneumonia. Clin Chim Acta. 2014 Jun 10;433C:272-277. doi: 10.1016/j.cca.2014.03.031. Epub 2014 Apr 8. Review. (SCI)

30.Ko CP, Yu YL, Hsiao PC, Yang SF, Yeh CB*. Plasma levels of soluble Axl correlate with severity of community-acquired pneumonia. Mol Med Rep. 2014 Apr;9(4):1400-4. doi: 10.3892/mmr.2014.1933. Epub 2014 Feb 6. (SCI)

31. Hsieh MC, Hsu HT, Hsiao PC, Yang SF, Yeh CB, Bien MY, Lin CH, Chien MH. Role of VEGF-C gene polymorphisms in susceptibility to hepatocellular carcinoma and its pathological development. J Clin Lab Anal. 2014 May;28(3):237-44. doi: 10.1002/jcla.21672. Epub 2014 Jan 29. (SCI)

32.Wang HL, Hsiao PC, Tsai HT, Yeh CB*, Yang SF*. Usefulness of plasma YKL-40 in management of community-acquired pneumonia severity in patients. Int J Mol Sci. 2013 Nov 19;14(11):22817-25. doi: 10.3390/ijms141122817. (SCI)

33. Chiang TC, Yu YL, Lin CW, Tsao SM, Yang SF, Yeh CB*. The circulating level of MMP-9 and its ratio to TIMP-1 as a predictor of severity in patients with community-acquired pneumonia. Clinica Chimica Acta 2013; 424C: 261-266. (SCI)

34..Wong CW, Tan WC, Yeh YT, Chou MC, Yeh CB*. Transarterial embolization for traumatic intractable oronasal hemorrhage. The Journal of Emergency Medicine 2013; 2013 Jun; 44(6):1088-91. (SCI)

35.Yeh CB, Hsieh MJ, Lin CW, Chiou HL, Lin PY, Chen TY*, Yang SF*. The antimetastatic effects of resveratrol on hepatocellular carcinoma through the downregulation of a metastasis-associated protease by SP-1 modulation. PLoS ONE 2013; 8: e56661. (SCI)

36. Wong RH, Huang CH, Yeh CB, Lee HS, Chien MH*, Yang SF*. Effects of metallothionein-1 genetic polymorphism and cigarette smoking on the development of hepatocellular carcinoma. Annals of Surgical Oncology 2013; 20: 2088-95. (SCI)

37.Ho SW, Yeh YT, Yeh CB*. Rupture of ectopic pelvic dysplastic kidney after blunt abdominal trauma presenting as left lower quadrant pain. The Journal of Emergency Medicine 2013; 44:e173-5. (SCI)

38.Yeh CB, Hsieh MJ, Hsieh YS, Chien MH, Lin PY, Chiou HL, Yang SF*. Terminalia Catappa Exerts Antimetastatic Effects on Hepatocellular Carcinoma through Transcriptional Inhibition of Matrix Metalloproteinase-9 by Modulating NF -κB and AP-1 Activity. Evidence-Based Complementary and Alternative Medicine. 2012; 595292. (SCI)

39.Yeh CB, Hsieh MJ, Hsieh YH, Chien MH, Chiou HL, Yang SF*. Antimetastatic effects of Norcantharidin on hepatocellular carcinoma by transcriptional inhibition of MMP-9 through modulation of NF-kB activity. PLoS ONE 2012; 7: e31055. (SCI)

40.Yeh CB, Lin PY, Hwang JM, Su CJ, Yeh YT, Yang SF, Chou MC*. Study on synthesis of thalidomide analogues and their bioactivities; inhibition on iNOS pathway and cytotoxic effects. Medicinal Chemistry Research 2012; 21: 953-963. (SCI)

41.Hsieh YS, Tsai CM, Yeh CB, Yang SF, Hsieh YH, Weng CJ*. Survivin T9809C, an SNP located in 3’-UTR, displays a correlation with the risk and clinicopathological development of hepatocellular carcinoma. Annals of Surgical Oncology 2012; 19: S625-S633. (SCI)

42.Chung TT, Yeh CB, Li YC, Su SC, Chien MH, Yang SF, Hsieh YH*. Effect of RECK gene polymorphisms on hepatocellular carcinoma susceptibility and clinicopathologic feature. PLoS ONE 2012; 7: e33517. (SCI) Contributed equally as first author

43.Su CK, Yeh KT, Yeh CB, Wang PH, Ho SC, Chou MC, Liu KC, Yang SF*, Yi YC*. Genetic polymorphism of the plasminogen activator inhibitor-1 is associated with an increased risk of endometrial cancer. J Surg Oncol 2011; 104: 755-759. (SCI)

44.Chien MH, Yeh CB, Li YC, Wei LH, Chang JH, Peng YT, Yang SF, Kuo WH*. Relationship of Interleukin-8 gene polymorphisms with hepatocellular carcinoma susceptibility and pathological development. J Surg Oncol 2011; 104: 798-803. (SCI)

45.Yeh CB, Su CJ, Hwang JM, Chou MC*. Therapeutic effects of cantharidin analogues without bridging ether oxygen on human hepatocellular carcinoma cells. Eur J Med Chem. 2010; 45: 3981-5. (SCI)

46.Yeh CB, Tsai HT, Chen YC, Kuo WH, Chen TY, Hsieh YH, Chou MC, Yang SF*. Genetic polymorphism of CCR2-64I increased the susceptibility of hepatocellular carcinoma. J  Surg Oncol 2010; 102: 264-270. (SCI)

46. Yeh CB. Circumferential Ischemic Injury with Occult Perforation of the Jejunum Following Seat Belt Trauma: Report of a Case. Formos J Surg 2009; 42:171-175

47.Yeh CB. Huge Urinary Bladder Rupture following Blunt Abdominal Trauma with Mimicking Imaging Presentation - Case report. J Emerg Med.2008; 10: 144-148.

48.Yeh CB. Epidemiology and Medical Costs of Patients with Hip Fracture at a Medical Center in Central Taiwan . J  Emerg Med. 2008; 10: 81-86.

 

 

 

 

 

 

聯絡方式

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 E-mail: ycb@csmu.edu.tw