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分類清單
研究領域

 

                     病理學科 101~106 年度研究計畫

 

主持人

年度

研究計畫名稱

計劃補助單位

許振東

101

探討乙醯半胱胺酸、前花青素及鈣離子阻斷對傷口癒合能力的治療效果與機制

中山醫學大學

附設醫院

102

探究龍葵水萃物對實驗性帕金森是否具保護作用及可能機轉

林偉隆

101

黃花蟛蜞菊功能性粗萃物抑制乳癌細胞增生及血管新生之活性及機制研究

中山醫學大學

附設醫院

103

Persantin 對脂多醣體誘導大鼠肝損傷之研究

104

樹葡萄水萃物預防酒精性發炎之研究

105

蘋果多酚對於卵巢切除母鼠之燙傷修護探討

106

建立慢性發炎動物模式研究嘉寶果預防酒精引起肝損傷與發炎之能力

韓志平

101

醫療機構執行新藥臨床試驗之多中心整合與品質及國際競爭力提升計畫

衛生福利部

探索上皮性卵巢癌的潛在治療標靶

科技部

102

醫療機構執行新藥臨床試驗多中心整合與品質及國際競爭力提升計畫

衛生福利部

103

醫療機構執行新藥臨床試驗多中心整合與品質及國際競爭力提升計畫

探索子宮頸癌的潛在治療標靶

中山醫學大學

附設醫院

104

探索子宮頸癌的可能之分子標記及分子機轉

趙婉如

103

探索上皮性卵巢癌的潛在治療標靶

中山醫學大學

附設醫院

104

探索黏液性卵巢癌的潛在治療相關分子標記

106

子宮頸癌症之訊息傳遞路徑、潛在樞紐基因突變與治療標靶之研究

李憶如

106

探討桑椹花青素萃物在第二型糖尿病引起的骨質疏鬆中調節骨質礦物畫的作用及機轉

科技部

 

許振東教授 論文著作

1. Lee YJ, Hsu JD, Lin WL, Kao SH, Wang CJ.,(2017), Upregulation of caveolin-1 by mulberry leaf extract and its major components, chlorogenic acid derivatives, attenuates alcoholic steatohepatitis via inhibition of oxidative stress. Food Funct. 8(1), 397-405.

2. Jao HY, Hsu JD, Lee YR, Lo CS, Lee HJ.,(2016), Mulberry water extract regulates the osteoblast/osteoclast balance in an ovariectomic rat model. Food Funct. 7(12), 4753-4763.

3. Chao WR, Lee MY, Ruan A, Sheng HP, Hsu JD, Han CP, Koo CL.,(2015), Assessment of HER2 Status Using Immunohistochemistry (IHC) and Fluorescence In Situ Hybridization (FISH) Techniques in Mucinous Epithelial Ovarian Cancer: A Comprehensive Comparison between ToGA Biopsy Method and ToGA Surgical Specimen Method. PLoS One. ,

4. Lu YH, Chang ST, Yang SF, Weng SF, Huang WT, Hsieh PP, Hsu JD, Tsou MH, Chuang SS.,(2015), Primary Intestinal Diffuse Large B-cell Lymphoma in Taiwan Showed a Relative Higher Rate of Perforation and EBV Association. Appl Immunohistochem Mol Morphol. Volume00, 1-9.

5. Yen JH, Lin LC, Chen MC, Sarang Z, Leong PY, Chang IC, Hsu JD, Chen JH, Hsieh YF, Pallai A, Köröskényi K, Szondy Z, Tsay GJ.,(2015), The metastatic tumor antigen 1-transglutaminase-2 pathway is involved in self-limitation of monosodium urate crystal-induced inflammation by upregulating TGF-β1. Arthritis Res Ther. 17, 65-65.

6. Jhuang JY1, Chang ST2, Weng SF3, Pan ST4, Chu PY5, Hsieh PP6, Wei CH7, Chou SC8, Koo CL9, Chen CJ10, Hsu JD11, Chuang SS12,(2014), Extranodal natural killer/T-cell lymphoma, nasal type in Taiwan: a relatively higher frequency of T-cell lineage and poor survival for extranasal tumors. Hum Pathol. 46, 313-321.

7. Wei YH1, Cheng JJ, Wu YH, Liu CY, Hung CJ, Hsu JD, Hsiao YP.,(2014), Necrobiotic xanthogranuloma: response to dapsone. Dermatol Ther. 28, 7-9.

8. Tsai ML, Huang HP, Hsu JD, Lai YR, Hsiao YP, Lu FJ, Chang HR.,(2014), Topical N-acetylcysteine accelerates wound healing in vitro and in vivo via the PKC/Stat3 pathway. Int J Mol Sci. 15(5), 7563-7578.

9. Wang RC, Chang ST, Hsieh YC, Huang WT, Hsu JD, Tseng CE, Wang MC, Hwang WS, Wang J, Chuang SS.,(2014), Spectrum of Epstein-Barr virus-associated T-cell lymphoproliferative disorder in adolescents and young adults in Taiwan. Int J Clin Exp Pathol. 7(5), 2430-2437.

10. Hsu LS, Chan CP, Chen CJ, Lin SH, Lai MT, Hsu JD, Yeh KT, Soon MS,(2013), Decreased Kruppel-like factor 4 (KLF4) expression may correlate with poor survival in gastric adenocarcinoma. Med Oncol. 30(4), 632-632.

11. Hsu TC, Tsai CC, Chiu CC, Hsu JD, Tzang BS. ,(2013), Exacerbating Effects of Human Parvovirus B19 NS1 on Liver Fibrosis in NZB/W F1 Mice. PLoS One. 8(6), 68393-68393.

12. Tsai CC, Chiu CC, Hsu JD, Hsu HS, Tzang BS, Hsu TC.,(2013), Human parvovirus B19 NS1 protein aggravates liver injury in NZB/W F1 mice. PLoS One. 8(3), 59724-59724.

13. Kuen-Daw Tsai, Jung-Chung Lin, Shu-mei Yang, Min-Jen Tseng, Jeng-Dong Hsu, Yi-Ju Lee, and Jaw-Ming Cherng,(2012), Curcumin Protects against UVB-Induced Skin Cancers in SKH-1 HairlessMouse: Analysis of EarlyMolecular Markers in Carcinogenesis. Evidence-Based Complementary and Alternative Medicine. 2012, 1-11.

14. Shyu LY, Chang HH, Lin DP, Teng YH, Lee HH.,(2012), Curcumin alleviates eosinophilic meningitis through reduction of eosinophil count following albendazole treatment against Angiostrongylus cantonensis in mice. PARASITOLOGY. 139(3), 358-365.

15. Chen CJ, Hsu LS, Lin SH, Chen MK, Wang HK, Lee H, Yeh KT.,(2012), Loss of nuclear expression of Krüppel-like factor 4 is associated with poor prognosis in patients with oral cancer. HUMAN PATHOLOGY. Epub ahead, 0-0.

16. Chen TH, Lin CC, Chen TY, Tsai MC,,(2011), An unusual endoscopic finding of gastric adenocarcinoma. Gastrointestinal Endoscopy . 74(5), 1145-1146.

17. Yun-Ching Chang \uc1\u-57310\'3f Jeng-Dong Hsu •Wea-Lung Lin Yi-Ju Lee Chau-Jong Wang,(2011), High incidence of acute promyelocytic leukemia specifically induced by N-nitroso-N-methylurea (NMU) in Sprague–Dawley rats. Archives of Toxicology. 86, 315-327.

18. Soon MS, Hsu LS, Chen CJ, Chu PY, Liou JH, Lin ,(2011), Expression of Kr\uc1\u-65167\'3fppel-like factor 5 in gastric cancer and its clinical correlation in Taiwan. Virchows Arch. 459(2), 161-166.

19. Lin WL, Kuo WH, Chen FL, Lee MY, Ruan A, Tyan YS, Chiang H, Han CP.,(2011), Identification of the Coexisting HER2 Gene Amplification and Novel Mutations in the HER2 Protein-Overexpressed Mucinous Epithelial Ovarian Cancer. ANNALS OF SURGICAL ONCOLOGY . 18(8), 2388-2394.

20. Tzang BS, Lin TM, Tsai CC, Yang LC, Hsu TC. ,(2011), Increased cardiac injury in NZB/W F1 mice received antibody against human parvovirus B19 VP1 unique region protein. MOLECULAR IMMUNOLOGY. 48(12-13), 1518-1524.

21. Ou TT, Wu CH, Chyau CC, Lee HJ, Wang CJ.,(2011), Paeonia lactiflora Pall inhibits bladder cancer growth involving phosphorylation of Chk2 in vitro and in vivo. JOURNAL OF ETHNOPHARMACOLOGY . 135(1), 162-172.

22. Kao SH, Ou TT, Chen YJ, Li YJ, Wang CJ.,(2011), Gallic acid induces G2/M phase arrest of breast cancer cell MCF-7 through stabilization of p27(Kip1) attributed to disruption of p27(Kip1)/Skp2 complex. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY . 59(5), 1996-2003.

23. Chang YC, Lin WL, Lee YJ, Wang CJ.,(2011), High incidence of acute promyelocytic leukemia specifically induced by N-nitroso-N-methylurea (NMU) in Sprague-Dawley rats. Arch Toxicol. 86(2), 315-327.

24. Chen PJ, Han CP.,(2010), Anti-cytokeratin CAM5.2 reagent (Becton Dickinson Biosciences) can detect CK 8, not CK8/18-Comment on "Sonographic findings in a patient with neurofibromatosis type 1 and a gastrointestinal stromal tumor,. JOURNAL OF CLINICAL ULTRASOUND . 38(7), 384-385.

25. Han CP, Hsu JD, Yao CC, Lee MY, Alexandra Ruan, Tyan YS, Yang SY, Hung Chiang.,(2010), HER2 gene amplification in primary mucinous ovarian cancer: a potential therapeutic target. Histopathology. ,

26. Chen CC, Hsu JD, Wang SF, Chiang HC, Yang MY, Kao ES, Ho YC, Wang CJ.,(2010), Hibiscus sabdariffa extract inhibits the development of atherosclerosis in cholesterol-fed rabbits. J Agric Food Chem. 51(18), 5472-5477.

27. Liu LC, Wang CJ, Lee CC, Su SC, Chen HL, Hsu JD, Lee HJ.,(2010), Aqueous extract of Hibiscus sabdariffa L. decelerates acetaminophen-induced acute liver damage by reducing cell death and oxidative stress in mouse experimental models. J Sci Food Agric. 90(2), 329-337.

28. Wu CH, Shih YW, Chang CH, Ou TT, Huang CC, Hsu JD, Wang CJ,(2010), EP(4) upregulation of Ras signaling and feedback regulation of Ras in human colon tissues and cancer cells. Arch Toxicol. ,

29. Cheng WC, Hsu JD, Yao CC, Han CP.,(2010), The murine monoclonal antibody anti-cytokeratin CAM 5.2 is specific for intracellular cytokeratin 8, not cytokeratin 18. J Thorac Cardiovasc Sur. 139(6), 1674-1675.

30. Wu TT, Tsai TW, Shen YT, Hsu JD, Yang LC, Li C.,(2010), Analyses of PRMT1 proteins in human colon tissues from Hirschsprung disease patients. Neurogastroenterol Motil. 22(9), 984-992.

31. Wu YL, Huang YF, Hsu JD, Han CP.,(2010), Becton Dickinson Biosciences CAM5.2 does not stand for true CK8/18. Comment on "Peripheral ameloblastoma in-situ: an evidential fact of surface epithelium origin". Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 109(5), 655-656.

 

韓志平教授 論文著作

1. Kok LF, Lee MY, Tyan YS, Wu TS, Cheng YW, Kung MF, Wang PW, *Han CP. Comparing the scoring mechanisms of p16INK4a immunohistochemistry based on independent nucleic stain and cytoplasmic stain in distinguishing between endocervical and endometrial adenocarcinomas in a tissue microarray study. ARCH GYNECOL OBSTET, 2010 Feb;281(2):293-300. (Corresponding author, SCI IF 1.279, Obstetrics & Gynecology, 56/78).

2. *Han CP, Kok LF, Lee MY, Wu TS, Ruan A, Cheng YW, Wang PW, Koo CL, *Tyan YS. Five commonly used markers (p53, TTF1, CK7, CK20, and CK34βE12) are of no use in distinguishing between primary endocervical and endometrial adenocarcinomas in a tissue microarray extension study. ARCH GYNECOL OBSTET, 2010 Feb;281(2):317-23.(1st & corresponding author, SCI IF 1.279, Obstetrics & Gynecology, 56/78)

3. Liao CL, Lee MY, Tyan YS, Kok LF, Wu TS, Koo CL, Wang PH, Chao KC and *Han CP. Progesterone receptor does not improve the performance and test effectiveness of the conventional 3-marker panel, consisting of estrogen receptor, vimentin and carcinoembryonic antigen in distinguishing between primary endocervical and endometrial adenocarcinomas in a tissue microarray extension study. J TRANSL MED, 2009 May 28;7:37.(Corresponding author, SCI IF 3.991, Medicine, Research & Experimental, 22/124)

4. *Han CP, Kok LF, Wang PH, Wu TS, Tyan YS, Cheng YW, *Lee MY, *Yang SF. Scoring of p16(INK4a) immunohistochemistry based on independent nuclear staining alone can sufficiently distinguish between endocervical and endometrial adenocarcinomas in a tissue microarray study. MODERN PATHOL, 2009 Jun;22(6):797-806. (1st & corresponding author, SCI IF 6.364,Pathology, 5/77)

5. *Han CP, Lee MY, Kok LF, Ruan A, Wu TS, Cheng YW, *Tyan YS, *Lin CY. Adding the p16(INK4a) marker to the traditional 3-marker (ER/Vim/CEA) panel engenders no supplemental benefit in distinguishing between primary endocervical and endometrial adenocarcinomas in a tissue microarray study. INT J GYNECOL PATHOL, 2009 Sep;28(5):489-96. (1st & corresponding author, SCI IF 1.631., OBSTETRICS & GYNECOLOGY, 44/78)

6. *Han CP, Lee MY, Kok LF, Wu TS, Cheng YW, Wang PH, Yue CH, *Tyan YS, A reappraisal of three-marker (ER/Vim/CEA), four-marker (ER/Vim/CEA/PR), and five-marker (ER/Vim/CEA/PR/p16INK4a) panels in the diagnostic distinction between primary endocervical and endometrial adenocarcinomas in a tissue microarray study. ARCH GYNECOL OBSTET, 2010 May;281(5):845-50. (1st & corresponding author, SCI IF 1.279, Obstetrics & Gynecology, 56/78)

7. Yao CC, Huang SM, Lin CC, Ho LC, Chang SW, Chen HM, Cheng YW, *Han CP. Assessment of common bile duct using laparoscopic ultrasound during laparoscopic cholecystectomy, Surgical Laparoscopy Endoscopy & Percutaneous Techniques, 2009 Aug;19(4):317-20.(Corresponding author, SCI IF 0.938, SURGERY,148/202)

8. *Han CP, Lee MY, Tyan YS, Kok LF, Yao CC, Wang PH, Hsu JD*, *Tseng SW. p16(INK4) and CEA can be mutually exchanged with confidence between both relevant three-marker panels (ER/Vim/CEA and ER/Vim/p16(INK4)) in distinguishing primary endometrial adenocarcinomas from endocervical adenocarcinomas in a tissue microarray study. VIRCHOWS ARCH, 2009 Oct; 455(4):353-61. (1st & corresponding author, SCI IF: 2.560, Pathology, 24/77)

9. Hsu JD, Yao CC, Lee MY, Kok LF, Wang PH, Tyan YS, *Han CP. True cytokeratin 8/18 immunohistochemistry is of no use in distinguishing between primary endocervical and endometrial adenocarcinomas in a tissue microarray study, INT J GYNECOL PATHOL, 2010;29: 282-9. (Corresponding author, SCI IF 1.631., OBSTETRICS & GYNECOLOGY, 44/78)

10. Yao CC, Tseng SW, *Han CP. Monoclonal antibody CAM5.2 can detect the cytokeratin 8, not cytokeratin 18. Comment on: "Occult disseminated tumor cells in lymph nodes of patients with gastric carcinoma. A critical appraisal of assessment and relevance. LANGENBECK ARCH SURG. 2009 Jan; 394(1): 105-113.". Langenbeck's Archives of Surgery 2010 Mar;395(3):291-2. (Corresponding author, SCI IF: 2.160, Surgery, 60/202)

11. Yi YC, Chou PT, Chen LY, Kuo WH, Ho ESC , *Han CP, *Yang SF. Matrix metalloproteinase-7 (MMP-7) polymorphism is a risk factor for endometrial cancer susceptibility. CLIN CHEM LAB MED. 2010 Mar;48(3):337-44. (Equally corresponding author, SCI IF 2.955, Medical Laboratory Technology, 5/29)

12. Hsu JD, Yao CC, Han LW, *Han CP. CAM5.2 is not identical to cytokeratins 8 and 18. AM J CLIN PATHOL, 2010 Mar;133(3):514. (Corresponding author, SCI IF: 3.005, Pathology, 18/77)

13. Hsu JD, Yao CC, Han LW, *Han CP. Anti-cytokeratin CAM5.2 is not a monoclonal antibody against cytokeratin 8/18. Clinical and Experimental Dermatology. 2010 Aug;35(6):672-3. (Corresponding author, SCI IF: 1.234, Dermatology, 41/61)

14. *Han CP, Hsu JD, Li YJ. Anticytokeratin CAM5.2 is not synonymous with CK8/18 monoclonal antibody; and anticytokeratin CAM5.2 can be a marker for cytokeratin 8 but not for cytokeratin 18 and 19. AM J SURG PATHOL, 2010 Apr;34(4):595. (1st & corresponding author, IF: 4.592, Surgery, 8/202)

15. Cheng WC, Hsu JD, Yao CC, *Han CP. The murine monoclonal antibody anti-cytokeratin CAM 5.2 is specific for intracellular cytokeratin 8, not cytokeratin 18. Journal of Thoracic And Cardiovascular Surgery.2010 Jun; 139(6):1674-5. (Corresponding author, SCI IF: 3.991, Surgery, 12/202).

16. Liao CL, Tzeng SL, Hsu JD, Chen PJ, *Han CP. BD (Becton, Dickinson and Company) Biosciences manufactures anticytokeratin CAM5.2, not CK8/18 monoclonal antibody. PATHOL INT. 2010 May;60(5):417. (Corresponding author, SCI IF: 1.585, Pathology ,53/77 )

17. Wang KC, Hsu JD, Yao CC, *Han CP. CAM5.2 (B.D.) is not synonymous with CK8/18 (Leica Microsystems). CYTOPATHOLOGY .2010 Aug; 21(4):277-8. (Corresponding author, SCI IF: 1.470, Pathology, 58/77)

18. Lin WL, Chen FL, *Han CP. Anti-cytokeratin CAM5.2 (BD Biosciences) and CK8 Give No Remarkable Advantages to the Pancytokeratin Cocktail of Antibodies (AE1/AE3, CAM5.2, MNF116, CK8, and CK18) in Detecting Disseminated Tumor Cells in Biologic Subtypes of Stage I–III Breast Cancer Patients. ANN SURG ONCOL. 2011 Dec;18 Suppl 3:261-2. Epub 2010 Dec 2. (Corresponding author, SCI IF: 4.459, Surgery, 13/202)

19. Wang SC, Chen FL, Lin WL, Wang PH, *Han CP. Cytokeratin 8/18 monoclonal antibody was dissimilar to anti-cytokeratin CAM 5.2. Comment on: "A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer. Cancer Chemother Pharmacol. 2010; 65(6): 1009-1021".Cancer Chemother Pharmacol. 2011 Jan;67(1):243-4; author reply 245. (Corresponding author, IF: 2.571, Pharmacology & Pharmacy, 107/254)

20. Tsai WC, Lee MY, Chen FL, Wang PH, Lin WL, Ruan A, Li YJ, Wang SC, Chiang H, *Han CP. The HER2 gene copies per tumor cell either before or after correction for chromosome-17 correlated significantly with HER2 IHC results in epithelial ovarian cancer in a tissue microarray study. ARCH GYNECOL OBSTET. 2011 Sep;284(3):721-9. (Corresponding author, SCI IF 1.279, Obstetrics & Gynecology, 56/78)

21. *Han CP. Retrocorneal membranes: a comparative immunohistochemical analysis of keratocytic, endothelial, and epithelial origins. AM J OPHTHALMOL, 2010 Nov;150(5):756. (1st & corresponding author, SCI 4.021, OPHTHALMOLOGY,5/58)

22. Tseng CJ, Lin YH, *Han CP. BD Pharmingen purified mouse anti-cytokeratin 7 monoclonal antibody (clone RCK105) should not be mistaken for BD Biosciences anti-cytokeratin CAM5.2 reagent (clone CAM 5.2). AM J OBSTET GYNECOL. 2011 Jan;204(1):e14. (Corresponding author, SCI IF 3.973, OBSTETRICS & GYNECOLOGY, 5/78)

23. Wang PH, Chen FL, Lin WL, Tyan YS, *Han CP. Cytokeratin 8/18 monoclonal antibody is dissimilar to anti-cytokeratin CAM 5.2 reagent - Comment on: "Oral metastatic hepatocellular carcinoma: A changing demographic in Europe and North America. Immunohistochemical advances in the microscopic diagnosis. Oral Oncol. 2010 Aug 20 [Epub ahead of print]”, Oral Oncol. 2011 Aug;47(8):775. (Corresponding author, SCI IF 3.029, DENTISTRY, ORAL SURGERY & MEDICINE, 5/82)

24. Leei CK, Lin WL, *Han CP. Monoclonal antibody Cam 5.2 targeted mainly CK8, but not CK18--Comment on: "Chromophobe renal cell carcinoma with liposarcomatous dedifferentiation--report of a unique case. Int J Clin Exp Pathol. 2010 May 5; 3 (5):534-40.". Int J Clin Exp Pathol. 2010 Aug 20; 3(7):742. (Corresponding author, IF: 1.783., Pathology, 40/77)

25. Chen PJ, Hsu JD, *Han CP. Anti-cytokeratin CAM5.2 reagent (Becton Dickinson Biosciences) can detect CK 8, not CK8/18-Comment on "Sonographic findings in a patient with neurofibromatosis type 1 and a gastrointestinal stromal tumor," J Clin Ultrasound 2010 Jan 20 [Epub ahead of print]. J CLIN ULTRASOUND. 2010 Sep;38(7):384. (Corresponding author, SCI IF 0.801, ACOUSTICS , 17/29)

26. Feng CY, Wang PH, Tsai HT, Tee YT, Ko JL, Chen SC, Lin CY, Han CP, Yang JS, Liu YF, Lin LY, Yang SF. Polymorphisms of human nonmetastatic clone 23 type 1 gene and neoplastic lesions of uterine cervix. Reprod Sci. 2010 Oct;17(10):886-93. Epub 2010 Jul 2. (SCI IF 2.179, Obstetrics & Gynecology, 26/78).

27. Wang PH, Yi YC, Tsai HT, Tee YT, Ko JL, Han CP, Liu YF, Lin LY, Yang SF. Significant association of genetic polymorphism of human nonmetastatic clone 23 type 1 gene with an increased risk of endometrial cancer. Gynecol Oncol. 2010 Oct;119(1):70-5. (SCI IF: 3.687, Surgery, Obstetrics & Gynecology, 7/78).

28. Hsu JD, Yao CC, Yuan CC, Lai CR, Ting LT, Li YJ, *Han CP. Anti-Cytokeratin CAM5.2 (BD) does not act as a substitute of the CK8/18 monoclonal antibody. Comment on: 'Expression of c-MET, low-molecular-weight cytokeratin, matrix metalloproteinases-1 and -2 in spinal chordoma'. Histopathology 2009; 54; 607-613. Histopathology. 2010

29. Wu YL, Huang YF, Hsu JD, *Han CP. Becton Dickinson Biosciences CAM5.2 does not stand for true CK8/18. Comment on "Peripheral ameloblastoma in-situ: an evidential fact of surface epithelium origin", Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:763-7. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 May;109(5):655-6. (Corresponding author, SCI IF 1.265, DENTISTRY, ORAL SURGERY & MEDICINE, 44/82)

30. Hsu JD, *Han CP. Anti-Cytokeratin CAM 5.2 (Becton Dickinson) is not synonymous with CK8/18 monoclonal antibody. Comment on "Pancreatic-type mixed acinar-endocrine carcinoma with alpha-fetoprotein production arising from the stomach: a report of an extremely rare case. Med Mol Morphol (2009) 42:167-174". Med Mol Morphol. 2010 Mar;43(1):65. (Corresponding author, SCI IF: 1.070, Pathology, 65/77)

31. *Han CP, Hsu JD, Koo CL, Yang SF. Antibody to cytokeratin (CK8/CK18) is not derived from CAM5.2 clone, and anticytokeratin CAM5.2 (Becton Dickinson) is not synonymous with the antibody (CK8/CK18). HUM PATHOL. 2010 Apr;41(4):616-7. (1st & corresponding author, SCI IF: 2.806, Pathology, 21/76)

32. Liao CL, Hsu JD, Lee MY, Kok LF, Li YJ, Wang PH, Yao CC, *Han CP. Distinguishing between primary endocervical and endometrial adenocarcinomas: is a 2-marker (Vim/CEA) panel enough? VIRCHOWS ARCH. 2010 Apr;456(4):377-86. (Corresponding author, SCI IF: 2.560, Pathology, 24/77)

33. Chen JT, Hsu JD, Yao CC, Han LW, *Han CP. Anti-cytokeratin CAM 5.2 does not act as a surrogate of the cytokeratin 8/18 monoclonal antibody. Comment on: "Utility of p63 in the differential diagnosis of atypical fibroxanthoma and spindle cell squamous cell carcinoma", in J Cutan Pathol 2009; 36: 543. J CUTAN PATHOL. 2010 Oct;37(10):1123-4. (Corresponding author, SCI IF: 1.560, Dermatology, 30/61)

34. Chen PJ, Hsu JD, *Han CP. Anti-cytokeratin CAM 5.2 is specific for K8 and to a lesser extent for the closely related K7, but shows no reactivity with K18 or K19: comment on: "keratin expression in endocrine organs and their neoplasms" Endocr Pathol. 2009 Spring; 20(1):1-10. Endocr Pathol. 2010 Mar;21(1):69-70. (Corresponding author, SCI IF: 1.715, Pathology, 51/77)

35. Lin CK, Yao CC, Tseng SW, *Han CP. Anti-Cytokeratin (CAM5.2) reagent directed against cytokeratin 8, not cytokeratin 18. Comment on "Improving staging accuracy in colon and rectal cancer by sentinel lymph node mapping: a comparative study. Eur J Surg Oncol. 2009; 35: 1065-1070." EJSO-EUR J SURG ONC. 2010 Apr;36(4):428. (Corresponding author, SCI IF: 2.892, Surgery, 31/202).

36. *Han CP, Hsu JD, Yao CC, Lee MY, Ruan A, Tyan YS, Yang SF, Chiang H. HER2 gene amplification in primary mucinous ovarian cancer: a potential therapeutic target. Histopathology. 2010 Nov;57(5):763-4. (1st &  Corresponding author, Corresponding author, SCI IF: 3.301., Pathology, 16/77)

37. Lin CK, Lin WL, Chen FL, *Lee MY, Kuo JF, Ruan A, Tyan YS, Chiang H, Chou MC, *Han CP. Assessing the impact of polysomy-17 on HER2 status as well as the correlations of HER2 status with prognostic variables (ER, PR, p53, Ki-67) in epithelial ovarian cancer: a tissue microarray study using immunohistochemistry and fluorescent in situ hybridization. INT J GYNECOL PATHOL, 2011; 30 (4):372-379. (Corresponding author, SCI IF 1.631., OBSTETRICS & GYNECOLOGY, 44/78 )

38. *Han CP, Lin WL, Wang PH, Yang SF, Lewis Jr JS, Chen CK, Ruan A, Kuo JF, Lee MY, Chiang H. Over-expression of c-KIT(CD117) occurs infrequently in squamous cell carcinoma of the uterine cervix. Histopathology (2010), Histopathology. 2011 May;58(6):988-990. doi: 10.1111/j.1365-2559.2011.03849.x. (1st &  Corresponding author, IF: 3.301., Pathology, 16/77)

39. Lin WL, Kuo WH, Chen FL, Lee MY, Ruan A, Tyan YS, Hsu JD, Chiang H, *Han CP. Identification of the Coexisting HER2 Gene Amplification and Novel Mutations in the HER2 Protein-Overexpressed Mucinous Epithelial Ovarian Cancer. ANN SURG ONCOL. 2011 Aug;18(8):2388-94. (Corresponding author, SCI IF: 4.459, Surgery, 13/202)

40. Kuo JF, Lin WL, *Han CP. Detection of minimal residual disease in blood and bone marrow in early stage breast cancer. CANCER-AM CANCER SOC. 2011 June 1st; 117 (11): 2578. doi: 10.1002/cncr.26089. (corresponding author, SCI IF: 4.901, Oncology, 38/202)

41. Lin WL, Chen FL, Kuo JF, Lee MY, *Han CP. Cytokeratin 8/18 monoclonal antibody was dissimilar to anti-cytokeratin CAM 5.2. - A comment on: "Discovery of two novel EWSR1/ATF1 transcripts in four chimerical transcripts-expressing clear cell sarcoma and their quantitative evaluation, Experimental and Molecular Pathology 90(2): 194-200, April 2011" Exp Mol Pathol. 2011 Aug;91(1):323-4. (corresponding author, SCI IF: 2.881, Pathology, 20/77 )

42. Lin WL, Chen FL, Lee MY, *Han CP. Source of anti-cytokeratin CAM 5.2 reagent. Int J Surg Pathol. 2011 Jun;19(3):409-10. (Corresponding author, SCI IF: 0.961, Surgery , 146/202)

43. Yao CC, Lin WL, Lee MY, *Han CP. Anti-Cytokeratin CAM 5.2 (B.D. Biosciences) has a primary reactivity with CK 7 and CK 8 (48 and 52 kD), rather than with the smaller molecular weight keratin breakdown fractions (50, 43, and 38 kD). ----- Comment on: Amemiya Y, Yang W, Benatar T, etc. "Insulin like growth factor binding protein-7 reduces growth of human breast cancer cells and xenografted tumors. BREAST CANCER RES TR, (2011), Nov;130(2):707-8. (Corresponding author, SCI IF: 4.198, Oncology , 49/202)

44. *Han CP, Lee MY. Anti-cytokeratin CAM5.2 monoclonal antibody reacted with both cytokeratin 7 and 8, but not cytokeratin 18. Comment on: Hepatocellular Carcinoma Metastatic to the Gingiva as a First Manifestation of Hepatocellular Carcinoma. J. Maxillofac. Oral Surg. (JMOSI), published on line: 25 February 2011; DOI 10.1007/s12663-011-0187-z; J. Maxillofac. Oral Surg. (JMOSI). 2011;10:366

45. *Han CP, Chen CK, Lin CK. Wang PH, Chiang H. Unusual c-KIT (+) squamous cell carcinoma of uterine cervix showing remarkable platelet-derived growth factor receptor, alpha subunit expression, but no activating mutation. Histopathology. 2011 Oct;59(4):788-790, doi: 10.1111/j.1365-2559.2011.03956.x. (1st & Corresponding author, IF: 3.301., Pathology, 16/77 )

46. Tee YT, Liu YF, Chang JT, Yang SF, Chen SC, Han CP, Wang PH, Liao CL. Single-nucleotide polymorphisms and haplotypes of membrane type 1-matrix metalloproteinase in susceptibility and clinical significance of squamous cell neoplasia of uterine cervix in Taiwan women. Reprod Sci. 2012 Sep;19(9):932-8. Epub 2012 Apr 23. (SCI IF 2.179, Obstetrics & Gynecology, 26/78)

47. Lee SH, Lin CY, Wang PH, Han CP, Yang SF, Chang JT, Lee MC, Lin LY, Lee MS. Significant association of elevated concentration of plasma YKL-40 with disease severity in patients with pelvic inflammatory disease. J Clin Lab Anal. 2012 May;26(3):136-42. doi: 10.1002/jcla.21500. (SCI IF 1.144, Medical Laboratory Technology, 22/29)

48. *Han CP, Huang YC, Lee MY, Chen EY, Wang PH, Chen CK. Anticytokeratin CAM5.2 should not be mistaken for CK8/18 monoclonal antibody. Comment on: CASE REPORT --- Spindle cell squamous cell carcinoma not expressing stratified but simple epithelial cytokeratin: Efficacy of simple epithelial cytokeratin immunoreactivity. Journal of Dermatology 2012; 39: 72–75. (1st & Corresponding author, SCI IF: 2.354., Dermatology, 14/61 )

49. Koo CL, Chao WR, Chen CK, *Han CP. CAM5.2 shows specific reactivity for cytokeratin 8, but less strict reactivity for the cytokeratin 7 and no reactivity for 18. ----- Comment on: “Fujikawa T, Tanaka A, Abe T et al. Undifferentiated carcinoma of the common bile duct with intraductal tumor thrombi: report of a case. Surg Today. 2011 Apr;41(4):579-84. Surg Today. 2013t; 43:1206-7. (Corresponding author, SCI IF: 1.208., Surgery, 119/102 )

50. Chao WR, Lin JC, Huang YC, Chen CK, *Han CP. Anticytokeratin CAM 5.2 Does not Correspond to Antibodies CK 8/18. Head Neck Pathol. 2013; 7:3 98-9. (Corresponding author )

51. Chao WR, *Han CP.Anti-cytokeratin CAM5.2 recognized CK8 mainly, but not CK18 --- Comment on “Early Assessment of Axillary Response with (18)F-FDG PET/CT during Neoadjuvant Chemotherapy in Stage II-III Breast Cancer: Implications for Surgical Management of the Axilla. Ann Surg Oncol. 2013 Jul; 20(7): 2227-35” ANN SURG ONCOL. 2014; 21: 699. (Corresponding author, SCI IF: 4.459, Surgery, 13/202)

52. Wu CH, Ko JL, Chen SC, Lin YW, Han CP, Yang TY, Chien MH, Wang PH. Clinical implications of aldo-keto reductase family 1 member C3 and its relationship with lipocalin 2 in cancer of the uterine cervix. Gynecol Oncol. 2014; 132:474-82. (SCI IF: 3.687, Surgery, 7/78)

53. Chao WR, Lee MY, Lin WL, Chen CK, Lin JC, Koo CL, Sheu GT, Han CP. HER2 amplification and overexpression are significantly correlated in mucinous epithelial ovarian cancer. Hum Pathol. 2014; 45: 810-6. . (Corresponding author, SCI IF: 2.806, Pathology, 21/76)

54. Chang KL, Chao WR, Han CP. Anticytokeratin (CAM5.2) reagent identifies cytokeratins 7 and 8, not cytokeratin 18. Chest. 2014; 145: 1441-2. (Corresponding author, SCI IF: 7.132, Respiratory System, 3/53)

55. Chao WR, Lee MY, Lin WL, Koo CL, Sheu GT, Han CP. Assessing the HER2 Status in Mucinous Epithelial Ovarian Cancer on the Basis of the 2013 ASCO/CAP Guideline Update. Am J Surg Pathol. 2014; 38: 1227-34. (Corresponding author, SCI IF: 4.592, Surgery, 8/202)

 

林偉隆副教授 論文著作

1. Yang SF, Liu YF, Cheng CW, Yang WE, Lin WL, Ko JL, Wang PH. Impact of microRNA-34a and polymorphism of its target gene CA9 on susceptibility to uterine cervical cancer. Oncotarget. 2017 Sep 12;8(44):77860-77871. doi: 10.18632/oncotarget.20842. eCollection 2017 Sep 29.

2. Chen TH, Yang SF, Liu YF, Lin WL, Han CP, Wang PH. Association of Fibroblast Growth Factor Receptor 4 Genetic Polymorphisms With the Development of Uterine Cervical Cancer and Patient Prognosis. Reprod Sci. 2018 Jan;25(1):86-93. doi: 10.1177/1933719117702250. Epub 2017 Apr 5.

3. Lee YJ, Hsu JD, Lin WL, Kao SH, Wang CJ. Upregulation of caveolin-1 by mulberry leaf extract and its major components, chlorogenic acid derivatives, attenuates alcoholic steatohepatitis via inhibition of oxidative stress. Food Funct. 2017 Jan 25;8(1):397-405. doi: 10.1039/c6fo01539e.

4. Tsai SC, Chen LH, Liao HH, Chiang CY, Lin WL, Chen SC, Tsao SM, Hung HC, Lee YT. Complicated skin and soft tissue infection with Mycobacterium fortuitum following excision of a sebaceous cyst in Taiwan. J Infect Dev Ctries. 2016 Dec 30;10(12):1357-1361. doi: 10.3855/jidc.7356.

5. Wu HH, Liu YF, Yang SF, Lin WL, Chen SC, Han CP, Wang HL, Lin LY, Wang PH. Association of single-nucleotide polymorphisms of high-mobility group box 1 with susceptibility and clinicopathological characteristics of uterine cervical neoplasia in Taiwanese women. Tumour Biol. 2016 Oct 4. [Epub ahead of print]

6. Tseng TH, Lin WL, Chen ZH, Lee YJ, Shie MS, Lee KF, Shen CH, Kuo HC9. Moniliformediquinone as a potential therapeutic agent, inactivation of hepatic stellate cell and inhibition of liver fibrosis in vivo. J Transl Med. 2016 Sep 9;14:263. doi: 10.1186/s12967-016-1022-6.

7. Tseng TH, Chien MH, Lin WL, Wen YC, Chow JM, Chen CK, Kuo TC, Lee WJ. Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1 expression. Environ Toxicol. 2016 Feb 12. doi: 10.1002/tox.22247. [Epub ahead of print]

8. Lin WL, Lai DY, Lee YJ, Chen NF, Tseng TH. Antitumor progression potential of morusin suppressing STAT3 and NFκB in human hepatoma SK-Hep1 cells. Toxicol Lett. 2015 Jan 22. 232(2): 490-98

9. Chao WR, Lin WL, Chen CK, Han LM, Lin JC, Han CP. Unusual c-KIT+ squamous cell carcinoma of the uterine cervix showing paradoxical hypermethylation of the c-KIT proto-oncogene. Eur J Obstet Gynecol Reprod Biol. 2015 Jan 01. 184: 150-51

10. Lin WL, Wang SM, Ho YJ, Kuo HC, Lee YJ, Tseng TH. Ethyl acetate extract of Wedelia chinensis inhibits tert-butyl hydroperoxide-induced damage in PC12 cells and D-galactose-induced neuronal cell loss in mice. BMC Complement Altern Med. 2014 Nov 15. 14(1): 491

11. Chen CK, Lee MY, Lin WL, Wang YT, Han CP, Yu CP, Chao WR. A qualitative study comparing the assay performance characteristics between the 2007 and the 2013 American Society for Clinical Oncology and College of American Pathologists HER2 scoring methods in mucinous epithelial ovarian cancer. Medicine (Baltimore). 2014 Nov 01. 93(27): 171

12. Chao WR, Lee MY, Lin WL, Koo CL, Sheu GT, Han CP. Assessing the HER2 status in mucinous epithelial ovarian cancer on the basis of the 2013 ASCO/CAP guideline update. Am J Surg Pathol. 2014 Sep 01. 38(9): 1227-34

13. Su YF, Wu TF, Ko JL, Tsai HT, Tee YT, Chien MH, Chou CH, Lin WL, Low HY, Chou MY, Yang SF, Wang PH. The expression of ribonucleotide reductase M2 in the carcinogenesis of uterine cervix and its relationship with clinicopathological characteristics and prognosis of cancer patients. PLoS One. 2014 May 17. 9(3): 91644

14. Tang CC, Lin WL, Lee YJ, Tang YC, Wang CJ. Polyphenol-rich extract of Nelumbo nucifera leaves inhibits alcohol-induced steatohepatitis via reducing hepatic lipid accumulation and anti-inflammation in C57BL/6J mice. Food Funct. 2014 Apr 01. 5(4): 678-87

15. Tsai MH, Hsiao YP, Lin WL, Tseng SW. Steatocystoma multiplex as initial impression of non-small cell lung cancer with complete response to gefitinib. Chin J Cancer Res. 2014 Feb; 26 (1):E5-9. doi: 10.3978/j.issn.1000-9604.2014.01.02.

16. Su YF, Wu TF, Ko JL, Tsai HT, Tee YT, Chien MH, Chou CH, Lin WL, Low HY, Chou MY, Yang SF, Wang PH. The expression of ribonucleotide reductase M2 in the carcinogenesis of uterine cervix and its relationship with clinicopathological characteristics and prognosis of cancer patients. PLoS One. 2014 Mar 17; 9 (3):e91644. doi: 10.1371/journal.pone.0091644. eCollection 2014.

17. Tang CC, Lin WL, Lee YJ, Tang YC, Wang CJ. Polyphenol-rich extract of Nelumbo nucifera leaves inhibits alcohol-induced steatohepatitis via reducing hepatic lipid accumulation and anti-inflammation in C57BL/6J mice. Food Funct. 2014 Apr; 5 (4).

18. Lin YC, Lu MC, Lin C, Chiang MK, Jan MS, Tang HL, Liu HC, Lin WL, Huang CY, Chen CM, Lai YC. Activation of IFN-γ/STAT/IRF-1 in hepatic responses to Klebsiella pneumoniae infection. PLoS One. 2013 Nov 6; 8 (11).

19. Ou TT, Lin MC, Wu CH, Lin WL, Wang CJ. Gallic acid attenuates oleic acid-induced proliferation of vascular smooth muscle cell through regulation of AMPK-eNOS-FAS signaling. Curr Med Chem. 2013; 20 (31):3944-53.

20. Ho HH, Chang CS, Ho WC, Liao SY, Lin WL, Wang CJ. Gallic acid inhibits gastric cancer cells metastasis and invasive growth via increased expression of RhoB, downregulation of AKT/small GTPase signals and inhibition of NF-κB activity. Toxicol Appl Pharmacol. 2013 Jan 1; 266 (1):76-85. doi: 10.1016/j.taap.2012.10.019. Epub 2012 Nov 13.

21. Yun-Ching Chang, Jeng-Dong Hsu, Wea-Lung Lin, Yi-Ju Lee & Chau-Jong Wang. High incidence of acute promyelocytic leukemia specifically induced by Nnitroso- N-methylurea (NMU) in Sprague– Dawley rats. Arch Toxicol. 2012, 86:315-327

22. Wea-Lung Lin, Yean-Jang Lee, Shao-Ming Wang, Pei-Yun Huang, Tsui-Hwa Tseng. Inhibition of cell survival, cell cycle progression, tumor growth and cyclooxygenase-2 activity in MDA-MB-231 breast cancer cells by camphorataimide B. European Journal of Pharmacology 680 (2012) 8–15

23. Lin WL, Kuo WH, Chen FL, Lee MY, Ruan A, Tyan YS, Hsu JD, Chiang H, Han CP. Identification of the Coexisting HER2 Gene Amplification and Novel Mutations in the HER2 Protein-Overexpressed Mucinous Epithelial Ovarian Cancer. Ann Surg Oncol. 2011 Aug;18(8):2388-94

24. Han CP, Lin WL, Wang PH, Yang SF, Lewis JS Jr, Chen CK, Ruan A, Kuo JF, Lee MY, Chiang H. Overexpression of c-KIT (CD117) occurs infrequently in squamous cell carcinoma of the uterine cervix. Histopathology. 2011 May; 58 (6):988-90.

25. Kuo JF, Lin WL, Han CP. Detection of minimal residual disease in blood and bone marrowin early stage breast cancer. Cancer. 2011 June; 117(11)2578.

26. Yao CC, Lin WL, Lee MY, Han CP. Anti-cytokeratin CAM 5.2 (B.D. Biosciences) has a primary reactivity with CK 7 and CK 8 (48 and 52 kD) rather than with the smallermolecular weight keratin breakdown fractions (50, 43, and 38 kD). Breast Cancer Res Treat. 2011 Jun 22.

27. Lin WL, Chen FL, Lee MY, Han CP. Source of Anti-Cytokeratin CAM 5.2 Reagent. Int J Surg Pathol. 2011 Jun; 19 (3):409-10.

28. Lin CK, Lin WL, Chen FL, Lee MY, Kuo JF, Ruan A, Tyan YS, Chiang H, Chou MC, Han CP. Assessing the Impact of Polysomy-17 on HER2 Status and the Correlations of HER2 Status With Prognostic Variables (ER, PR, p53, Ki-67) in Epithelial Ovarian Cancer: A Tissue Microarray Study Using Immunohistochemistry and Fluorescent In Situ Hybridization. Int J Gynecol Pathol. 2011 Jul; 30(4): 372- 379.

29. Lin WL, Chen FL, Kuo JF, Lee MY, Han CP. Cytokeratin 8/18 monoclonal antibody was dissimilar to anti-cytokeratin CAM 5.2. - A comment on: "Discovery of two novel EWSR1/ATF1 transcripts in four chimerical transcripts-expressing clear cell sarcoma and their quantitative evaluation. Exp Mol Pathol. 2011 Apr 13; 91 (1):323-324.

30. Liu HC, Jan MS, Lin YC, Lin WL, Wu TC, Huang CN, Chen CM. and Lu MC. A rare pulmonary zygomycosis mainifested as chronic mediastinitis and bronchial perforation. Eur Respir J 2011; 38: 1–2.

31. Wang SC, Chen FL, Lin WL, Wang PH, Han CP. Cytokeratin 8/18 monoclonal antibody was dissimilarto anti-cytokeratin CAM 5.2. Comment on: ‘‘A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer. Cancer Chemother Pharmacol. 2011 Jan; 67 (1):243-4.

32. Lin WL ,Tsai CH ,Liu CL ,Yang LC ,Chao WR. Bilateral cervical ectopic thymic nodules with accessory thyroid tissue and an ectopic parathyroid in the neck region. J Dent Sci 2011;6:61-64

 

趙婉如助理教授 論文著作

1. Chao, W.R., J.C. Lin, Y.C. Huang, C.K. Chen, and C.P. Han, Anticytokeratin CAM 5.2 does not correspond to antibodies CK 8/18. Head Neck Pathol, 2013. 7(4): p. 398-9. (First author & Corresponding author)

2. Koo, C.L., W.R. Chao, C.K. Chen, and C.P. Han, CAM 5.2 shows specific reactivity for cytokeratin 8, but less strict reactivity for cytokeratin 7 and no reactivity for cytokeratin 18: in response to "Fujikawa T, Tanaka A, Abe T et al. 'Undifferentiated carcinoma of the common bile duct with intraductal tumor thrombi: report of a case'. Surg today 2011;41(4):579-84.". Surg Today, 2013. 43(10): p. 1206-7. (Corresponding author, SCI, IF1.745, SURGERY, 98/196=50%)

3. Chang, K.L., W.R. Chao, and C.P. Han, Anticytokeratin (CAM5.2) reagent identifies cytokeratins 7 and 8, not cytokeratin 18. Chest, 2014. 145(6): p. 1441-1442. (Corresponding author, SCI, IF6.044, RESPIRATORY SYSTEM, 7/59=11.86%)

4. Chao, W.R. and C.P. Han, Anti-cytokeratin CAM5.2 recognized CK8 mainly, but not CK18: comment on "Early assessment of axillary response with 18F-FDG PET/CT during neoadjuvant chemotherapy in stage II-III breast cancer: implications for surgical management of the axilla. Annals of Surgical Oncology doi: 10.1245/s10434-013-2902-0 (2013)". Ann Surg Oncol, 2014. 21(2): p. 699. (First author & Corresponding author, SCI, IF4.041, SURGERY, 17/196=8.67%)

5. Chao, W.R., M.Y. Lee, W.L. Lin, C.K. Chen, J.C. Lin, C.L. Koo, G.T. Sheu, and C.P. Han, HER2 amplification and overexpression are significantly correlated in mucinous epithelial ovarian cancer. Hum Pathol, 2014. 45(4): p. 810-6. (First author & Corresponding author, SCI, IF3.014, PATHOLOGY, 18/79=22.78%)

6. Chao, W.R., M.Y. Lee, W.L. Lin, C.L. Koo, G.T. Sheu, and C.P. Han, Assessing the HER2 status in mucinous epithelial ovarian cancer on the basis of the 2013 ASCO/CAP guideline update. Am J Surg Pathol, 2014. 38(9): p. 1227-34. (First author & Corresponding author, SCI, IF5.363, SURGERY, 8/196=4.08%)

7. Chao, Y.H., H.P. Wu, K.H. Wu, Y.G. Tsai, C.T. Peng, K.C. Lin, W.R. Chao, M.S. Lee, and Y.C. Fu, An increase in CD3+CD4+CD25+ regulatory T cells after administration of umbilical cord-derived mesenchymal stem cells during sepsis. PLoS One, 2014. 9(10): p. e110338. (Corresponding author, SCI, IF2.806, MULTIDISCIPLINARY SCIENCES, 15/64=23.43%)

8. Chen, C.K., M.Y. Lee, W.L. Lin, Y.T. Wang, C.P. Han, C.P. Yu, and W.R. Chao, A qualitative study comparing the assay performance characteristics between the 2007 and the 2013 American Society for Clinical Oncology and College of American Pathologists HER2 scoring methods in mucinous epithelial ovarian cancer. Medicine (Baltimore), 2014. 93(27): p. e171. (Corresponding author, SCI, IF1.803, MEDICINE, GENERAL & INTERNAL, 58/154=37.66%)

9. Chang, S.W., W.R. Chao, A. Ruan, P.H. Wang, J.C. Lin, and C.P. Han, A promising hypothesis of c-KIT methylation/ expression paradox in c-KIT (+) squamous cell carcinoma of uterine cervix ----- CTCF transcriptional repressor regulates c-KIT proto-oncogene expression. Diagn Pathol, 2015. 10: p. 207. (Corresponding author, SCI, IF2.087, PATHOLOGY, 34/79=43.03%)

10. Chao, W.R., M.Y. Lee, A. Ruan, H.P. Sheng, J.D. Hsu, C.P. Han, and C.L. Koo, Assessment of HER2 Status Using Immunohistochemistry (IHC) and Fluorescence In Situ Hybridization (FISH) Techniques in Mucinous Epithelial Ovarian Cancer: A Comprehensive Comparison between ToGA Biopsy Method and ToGA Surgical Specimen Method. PLoS One, 2015. 10(11): p. e0142135. (First author & Corresponding author, SCI, IF2.806, MULTIDISCIPLINARY SCIENCES, 15/64=23.43%)

11. Chao, W.R., W.L. Lin, C.K. Chen, L.M. Han, J.C. Lin, and C.P. Han, Unusual c-KIT+ squamous cell carcinoma of the uterine cervix showing paradoxical hypermethylation of the c-KIT proto-oncogene. Eur J Obstet Gynecol Reprod Biol, 2015. 184: p. 130-1. (First author & Corresponding author, SCI, IF1.666, OBSTETRICS & GYNECOLOGY, 46/80=57.5%)

12. Lin, Y.L., K.F. Chang, X.F. Huang, C.L. Hung, S.C. Chen, W.R. Chao, K.W. Liao, and N.M. Tsai, Liposomal n-butylidenephthalide protects the drug from oxidation and enhances its antitumor effects in glioblastoma multiforme. Int J Nanomedicine, 2015. 10: p. 6009-20. (Corresponding author, SCI, IF4.300, PHARMACOLOGY & PHARMACY, 37/256=14.45%)

13. Yang, L.C., Y.P. Hsiao, C.T. Lu, C.H. Huang, W.R. Chao, Y.T. Lin, H.A. Su, S.L. Chang, and J.G. Chung, Xeroderma pigmentosum complementation group C protein (XPC) expression in basal cell carcinoma. In Vivo, 2015. 29(1): p. 35-8. (Corresponding author, SCI, IF0.953, MEDICINE, RESEARCH & EXPERIMENTAL, 107/128=83.59%)

14. Chang, K.L., M.Y. Lee, W.R. Chao, and C.P. Han, The status of Her2 amplification and Kras mutations in mucinous ovarian carcinoma. Hum Genomics, 2016. 10(1): p. 40. (Corresponding author, SCI, IF3.327, GENETICS & HEREDITY, 61/166=36.74%)

15. Chao, W.R., C.K. Chen, L.M. Han, and C.P. Han, Mutation-free expression of c-Kit proto-oncogene in primary adenocarcinoma of uterine cervix. Taiwan J Obstet Gynecol, 2016. 55(5): p. 741-742. (First author & Corresponding author, SCI, IF0.925, OBSTETRICS & GYNECOLOGY, 73/80=91.25%)

16. Hsiao, Y.P., C.T. Lu, J. Chang-Chien, W.R. Chao, and J.J. Yang, Advances and Applications of Ion Torrent Personal Genome Machine in Cutaneous Squamous Cell Carcinoma Reveal Novel Gene Mutations. Materials (Basel), 2016. 9(6). (Corresponding author, SCI, IF2.654, MATERIALS SCIENCE, MULTIDISCIPLINARY, 82/275=29.81%)

17. Lee, Y.J., M.Y. Lee, A. Ruan, C.K. Chen, H.P. Liu, C.J. Wang, W.R. Chao, and C.P. Han, Multipoint Kras oncogene mutations potentially indicate mucinous carcinoma on the entire spectrum of mucinous ovarian neoplasms. Oncotarget, 2016. 7(50): p. 82097-82103. (Corresponding author, SCI, IF5.168, ONCOLOGY, 44/217=20.27%)

18. Wu, K.H., H.P. Wu, W.R. Chao, W.Y. Lo, P.C. Tseng, C.J. Lee, C.T. Peng, M.S. Lee, and Y.H. Chao, Time-Series Expression of Toll-Like Receptor 4 Signaling in Septic Mice Treated with Mesenchymal Stem Cells. Shock, 2016. 45(6): p. 634-40. (Corresponding author, SCI, IF3.113, SURGERY, 40/196= 20.40%)

19. Chao, Y.H., K.H. Wu, C.W. Lin, S.F. Yang, W.R. Chao, C.T. Peng, and H.P. Wu, PG2, a botanically derived drug extracted from Astragalus membranaceus, promotes proliferation and immunosuppression of umbilical cord-derived mesenchymal stem cells. J Ethnopharmacol, 2017. 207: p. 184-191. (Corresponding author, SCI, IF2.981, PHARMACOLOGY & PHARMACY, 89/256=34.76%)

 

李憶如助理教授 論文著作

1.    Huang CN, Wang CJ, Lee YJ, Peng CH. (2017, Jul). Active subfractions of Abelmoschus esculentus substantially prevent free fatty acid-induced β cell apoptosis via inhibiting dipeptidyl peptidase-4.. PLoS One., 12 (7): e0180285..

2.    Lee YJ,Jeng-Dong Hsu, Wea-Lung Lin, Shao-Hsuan Kao and Chau-Jong Wang  (2017, Feb). Upregulation of caveolin-1 by Mulberry leaf extract and its major components chlorogenic acid derivatives attenuates alcoholic steatohepatitis via inhibition of oxidative stress. Food Function, 8 (1): 397-405.

3.    Dai-Jung Chung, Mon-Yuan Yang, Yi-Ru Li, Wei-Jen Chen, Chiu-Ya Hung, Chau-Jong Wang (2017, Jan). Ganoderma lucidum repress injury of ethanol- induced steatohepatitis via anti-inflammation, anti-oxidation and reducing hepatic lipid in C57BL/6J mice . Journal of Functional Foods, (2017) 314-322.

4.    Yan SL, Wang ZH, Yen HF, Lee YJ, Yin MC (2017, Jan). Corrigendum to "Reversal of ethanol-induced hepatotoxicity by cinnamic and syringic acids in mice". Food and Chemical Toxicology, 99 (2017) 242.

5.    Chan KC, Yu MH, Lin MC, Huang CN, Chung DJ, Lee YJ, Wu CH, Wang CJ (2016, Dec). Pleiotropic effects of acarbose on atherosclerosis development in rabbits are mediated via upregulating AMPK signals.. Scientific Reports, 6: 38642.

6.    Jao HY, Hsu JD, Lee YR, Lo CS, Lee HJ (2016, Dec). Mulberry water extract regulates the osteoblast/osteoclast balance in an ovariectomic rat model.. Food and Function, 7 (12): 4753-4763..

7.    Lee YJ, Lee MY, Ruan A, Chen CK, Liu HP, Wang CJ, Chao WR, Han CP (2016, Nov). Multipoint Kras oncogene mutations potentially indicate mucinous carcinoma on the entire spectrum of mucinous ovarian neoplasms. Oncotarget, 7 (50): 82097-82103..

8.    Hsu YM, Hung YC, Hu L, Lee YJ, Yin MC (2015, Dec). Anti-Diabetic Effects of Madecassic Acid and Rotundic Acid.. Nutrients, 7 (12): 10065-75..

9.    Yang MY, Chan KC, Lee YJ, Chang XZ, Wu CH, Wang CJ. (2015, May). Sechium edule Shoot Extracts and Active Components Improve Obesity and a Fatty Liver That Involved Reducing Hepatic Lipogenesis and Adipogenesis in High-Fat-Diet-Fed Rats.. Journal of Agricultural and Food Chemistry, 63 (18):  4587-96..

10.  Yan SL, Yang HT, Lee YJ, Lin CC, Chang MH, Yin MC (2014, May). Asiatic acid ameliorates hepatic lipid accumulation and insulin resistance in mice consuming a high-fat diet.. Journal of Agricultural and Food Chemistry, 62 (20): 4625-31..

11.   Tang CC, Lin WL, Lee YJ, Tang YC, Wang CJ (2014, Apr). Polyphenol-rich extract of Nelumbo nucifera leaves inhibits alcohol-induced steatohepatitis via reducing hepatic lipid accumulation and anti-inflammation in C57BL/6J mice.. Food and Function, 5 (4):678-87..

12.   Tang CC, Huang HP, Lee YJ, Tang YH, Wang CJ (2013, Dec). Hepatoprotective effect of mulberry water extracts on ethanol-induced liver injury via anti- inflammation and inhibition of lipogenesis in C57BL/6J mice.. Food and Chemical Toxicology, 62:786-96..

13.   Chan KC, Yang MY, Lin MC, Lee YJ, Chang WC, Wang CJ (2013, Mar). Mulberry leaf extract inhibits the development of atherosclerosis in cholesterol- fed rabbits and in cultured aortic vascular smooth muscle cells. Journal of Agricultural and Food Chemistry, 61(11):2780-8..