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宋文瑋 助理教授

Wen-Wei Sung, M.D., Ph.D.


實驗室 研究大樓七樓/行政大樓二樓

電話 (04) 2473-9595 ext.34803

傳真 (04) 24728098



現任:中山醫學大學醫學系 助理教授 (2017.08 ~)

           中山醫學大學附設醫院泌尿科 住院醫師 (2017.08 ~)


學歷:中山醫學大學醫學系(醫學士-博士學程) 醫學士-博士 (2016.06)


研究興趣: 腫瘤免疫學、癌症生物學、轉譯醫學、泌尿生殖生理學


導生時間(office hour) (每月因臨床工作調整)

106年10、11月:每周二、五 (13:30~14:50); 12月:每周三、五 (8:30~12:00) 於附設醫院核子醫學大樓3F,泌尿科門診區檢查室



  1. International Journal of Cancer

  2. Cancer

  3. Oncotarget

  4. Tumor Biology


  6. EBioMedicine

  7. Journal of Clinical Pathology

  8. JSM Surgical Oncology and Research

  9. Journal of Clinical & Experimental Cardiology

  10. Journal of Clinical Trials

  11. Biomedical Research

  12. Advanced Materials Science Research

  13. Journal of Medical & Surgical Pathology

  14. Journal of Gastroenterology and Its Complications

  15. Acta Medica Philippina



2017:住院醫師研究表現傑出獎 (住院醫師第一年)

2016:住院醫師研究表現傑出獎 (PGY醫師)

2011-2012:教育部獎助醫師科學家 (博士班第三年)

2010-2011:教育部獎助醫師科學家 (博士班第二年)

2009-2010:教育部獎助醫師科學家 (博士班第一年)


學術著作 (以下文章皆為SCI文章)


  1. Tsai MC, Wang CC, Lee HL, Peng CM, Yang TW, Chen HY, Sung WW*, Lin CC*. Health Disparities Are Associated with Gastric Cancer Mortality-To-Incidence Ratios in 57 Countries. World J Gastroenterol. Accept, In production. (*corresponding author)

   2. Wang CC, Tsai MC, Peng CM, Lee HL, Chen HY, Yang TW, Sung WW*, Lin CC*. Favorable Liver Cancer Mortality-To-Incidence Ratios of Countries with High Health Expenditure. Eur J Gastroenterol Hepatol. Accept, In production. (*corresponding author)

   3. Wang SC*, Sung WW*, Kao YL, Hsieh TY, Chen WJ, Chen SL, Chang HR. The gender difference and mortality-to-incidence ratio relate to health care disparities in bladder cancer: National estimates from 33 countries. Sci Rep. 2017 Jun 28;7(1):4360. (*equal contribution)

   4. Hsu LS, Huang RH, Lai HW, Hsu HT, Sung WW, Hsieh MJ, Wu CY, Lin YM, Chen MK, Lo YS, Chen CJ. KLF6 inhibited oral cancer migration and invasion via downregulation of mesenchymal markers and inhibition of MMP-9 activities. Int J Med Sci. 2017 Apr 9;14(6):530-535.

   5. Chen CJ, Sung WW, Chen HC, Chern YJ, Hsu HT, Lin YM, Lin SH, Peck K*, Yeh KT*. Early Assessment of Colorectal Cancer by Quantifying Circulating Tumor Cells in Peripheral Blood. Int J Mol Sci. 2017 Mar 31;18(4). pii: E743.

   6. Su HA, Sun PL, Sung WW, Cheng SY, Chang HC, Yang JH, Hsiao YP. Deep Dermatophytosis Caused by Zoophilic Strain of Trichophyton interdigitale with Successful Treatment of Itraconazole. Mycopathologia. 2017 Feb 2; Epub ahead of print.

   7. Chen SL, Wang SC, Ho CJ, Kao YL, Hsieh TY, Chen WJ, Chen CJ, Wu PR, Ko JL, Lee H, Sung WW*. Prostate Cancer Mortality-To-Incidence Ratios Are Associated with Cancer Care Disparities in 35 Countries. Sci Rep. 2017 Jan 4;7:40003. (*corresponding author)


   8. Chang CF, Chen SL, Sung WW, Hsieh MJ, Hsu HT, Chen LH, Chen MK, Ko JL, Chen CJ, Chou MC. PBK/TOPK Expression Predicts Prognosis in Oral Cancer. Int J Mol Sci. 2016 Jun 24;17(7). pii: E1007.

   9. Chiu LY, Hsin IL, Yang TY, Sung WW, Chi JY, Chang JT, Ko JL, Sheu GT. The ERK-ZEB1 pathway mediates epithelial-mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids. Oncogene. 2016 Jun 6; 36(2):242-253.

   10. Lee CH, Chen SL, Sung WW, Lai HW, Hsieh MJ, Yen HH, Su TC, Chiou YH, Chen CY, Lin CY, Chen ML*, Chen CJ*. The Prognostic Role of STEAP1 Expression Determined via Immunohistochemistry Staining in Predicting Prognosis of Primary Colorectal Cancer: A Survival Analysis. Int J Mol Sci. 2016 Apr 19;17(4). pii: E592.

   11. Yeh CM*, Sung WW*, Lai HW, Hsieh MJ, Yen HH, Su TC, Chang WH, Chen CY, Ko JL, Chen CJ. Opposing Prognostic Roles of Nuclear and Cytoplasmic RACGAP1 Expression in Colorectal Cancer Patients. Hum Pathol. 2016 Jan;47(1):45-51. (*equal contribution)


   12. Lin YM*, Sung WW*, Hsieh MJ, Tsai SC, Lai HW, Yang SM, Shen KH, Chen MK, Lee H, Yeh KT, Chen CJ. High PD-L1 Expression Correlates with Metastasis and Poor Prognosis in Oral Squamous Cell Carcinoma. PLoS One. 2015 Nov 12;10(11):e0142656. (*equal contribution)

   13. Hwang JC, Sung WW, Tu HP, Hsieh KC, Yeh CM, Chen CJ, Tai HC, Hsu CT, Shieh GS, Chang JG, Yeh KT, Liu TC. The Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma. PLoS One. 2015 Oct 2;10(10):e0139435.


   14. Sung WW, Lin YM, Wu PR, Yen HH, Lai HW, Su TC, Huang RH, Wen CK, Chen CY, Chen CJ, Yeh KT. High nuclear/cytoplasmic ratio of Cdk1 expression predicts poor prognosis in colorectal cancer patients. BMC Cancer. 2014 Dec 15;14:951. 

   15. Wu DW, Chuang CY, Lin WL, Sung WW, Cheng YW, Lee H. Paxillin promotes tumor progression and predicts survival and relapse in oral cavity squamous cell carcinoma by microRNA-218 targeting. Carcinogenesis. 2014 Aug;35(8):1823-9.


   16. Sung WW and Lee H. The Role of Interleukin-10 in Tumor Progression of Human Papillomavirus-Associated Non-Small Cell Lung Cancer. OncoImmunology. 2013 Sep 1;2(9):e25854.

   17. Sung WW, Wang YC, Lin PL, Cheng YW, Chen CY, Wu TC, Lee H. IL-10 Promotes Tumor Aggressiveness via Upregulation of CIP2A Transcription in Lung Adenocarcinoma. Clin Cancer Res. 2013 Aug 1;19(15):4092-103. (CCR Highlights)

   18. Wang YC*, Sung WW*, Wang L, Cheng YW, Chen CY, Wu TC, Shieh SH, Lee H. Different Impact of IL10 Haplotype on Prognosis in Lung Squamous Cell Carcinoma and Adenocarcinoma. Anticancer Res. 2013 Jun;33(6):2729-35. (*equal contribution)

   19. Tang SC, Wu CH, Lai CH, Sung WW, Yang WJ, Tang LC, Hsu CP, Ko JL. Glutathione s-transferase mu2 suppresses cancer cell metastasis in non-small cell lung cancer. Mol Cancer Res. 2013 May;11(5):518-29.

   20. Chen CJ, Sung WW, Su TC, Chen MK, Wu PR, Yeh KT, Ko JL, Lee H. High expression of interleukin 10 might predict poor prognosis in early stage oral squamous cell carcinoma patients. Clin Chim Acta. 2013 Jan 16;415:25-30.


   21. Chen CJ, Sung WW, Lin YM, Chen MK, Lee CH, Lee H, Yeh KT, Ko JL. Gender difference in the prognostic role of interleukin 6 in oral squamous cell carcinoma. PLoS One. 2012;7(11):e50104. 

   22. Chuang CY*, Sung WW*, Wang L, Lin WL, Yeh KT, Su MC, Hsin CH, Lee SY, Wu BC, Cheng YW, Lee H. Differential impact of IL-10 expression on survival and relapse between HPV16-positive and -negative oral squamous cell carcinomas. PLoS One. 2012;7(10):e47541. (*equal contribution)

   23. Chen TH, Huang CC, Yeh KT, Chang SH, Chang SW, Sung WW, Cheng YW, Lee H. Human papilloma virus 16 E6 oncoprotein associated with p53 inactivation in colorectal cancer. World J Gastroenterol. 2012 Aug 14;18(30):4051-8.

   24. Wang YC*, Sung WW*, Wu TC, Wang L, Chien WP, Cheng YW, Chen CY, Shieh SH, Lee H. Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer. PLoS One. 2012;7(7):e39525. (*equal contribution)

   25. Tsai LL, Yu CC, Lo JF, Sung WW, Lee H, Chen SL, Chou MY. Enhanced cisplatin resistance in oral-cancer stem-like cells is correlated with upregulation of excision-repair cross-complementation group 1. J Dent Sci. 2012 Jun; 7(2):111–7.


   26. Sung WW, Wang YC, Cheng YW, Lee MC, Yeh KT, Wang J, Chen CY, Lee H. A polymorphic -844T/C in fasl promoter predicts survival and relapse in non-small cell lung cancer. Clin Cancer Res. 2011 Sep 15;17(18):5991-9. (CCR Highlights)


更新日期: 2017/09/05